Vaccination of poultry infected with multiple Salmonella serovars

感染多种沙门氏菌血清型的家禽的疫苗接种

• 批准号: LP230100209
• 负责人: Prof Kapil Chousalkar
• 金额: $ 49.55万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2024
• 资助国家: 澳大利亚
• 起止时间: 2024-01-01 至 2027-12-31
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP230100209
• 关键词: Vaccination; poultry; infected; multiple; Salmonella

Salmonella is a zoonotic, foodborne pathogen found on eggs and poultry meat. It is the second largest cause of human gastrointestinal disease, thus, reduction of Salmonella on poultry farms is paramount to public health. This project aims to evaluate the long-term efficacy of a commercial Salmonella Typhimurium vaccine against multiple serotypes, including the emerging Salmonella Enteritidis. This project will generate new knowledge in avian immunology using an innovative approach to evaluate the host response to multi-serovar infection. Outcomes of this project will future proof the Australian poultry industry against exotic Salmonella serotypes benefitting the industry by significantly reducing risks of future outbreaks and economic loss.

沙门氏菌是一种人畜共患的食源性病原体，存在于鸡蛋和禽肉中。它是人类胃肠道疾病的第二大原因，因此，减少家禽养殖场的沙门氏菌对公共卫生至关重要。该项目旨在评价商业鼠伤寒沙门氏菌疫苗对多种血清型（包括新出现的沙门氏菌肠炎）的长期有效性。该项目将产生新的知识，在鸟类免疫学使用创新的方法来评估多血清型感染的主机响应。该项目的成果将在未来证明澳大利亚家禽业对外来沙门氏菌血清型的抵抗力，通过显着降低未来爆发的风险和经济损失使该行业受益。