Peru Vanderbilt – PREvention through VacciNation Training (PREVENT) program

秘鲁范德比尔特 — 通过疫苗接种培训进行预防 (PREVENT) 计划

• 批准号: 10674393
• 负责人: CARLOS G GRIJALVA
• 金额: $ 25.14万
• 依托单位: VANDERBILT UNIVERSITY MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-05-01 至 2027-12-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10674393
• 关键词: Academic Medical Centers; Address; Authorization documentation; Biological; Communicable Diseases; Data; Developing Countries; Development; Disease; Doctor of Philosophy; Ensure; Evaluation; Faculty; Fellowship; Future; Goals; Grant; Growth; Herd Immunity; Immunization Programs; Knowledge; Lead; Mentors; Modernization; Peru; Pharmacoepidemiology; Prevention; Process; Productivity; Program Evaluation; Research; Research Personnel; Scientist; Structure; Technical Expertise; Training; Training Programs; Vaccination; Vaccines; antimicrobial resistant infection; authority; distrust; implementation evaluation; low and middle-income countries; multidisciplinary; pressure; programs; success; tool; unvaccinated; vaccine development; vaccine trial; vaccinology

SUMMARY While vaccination is the most efficient tool for the prevention of infectious diseases both in developed and developing countries, the implementation of effective vaccination programs is challenging. The development, introduction and implementation of effective vaccination depends on availability of locally generated evidence, especially data required by local regulatory authorities. An essential requirement to make this happen is to have well-trained local researchers who have a clear understanding of the process behind vaccine development, vaccine introduction and program implementation. Training of researchers on the achieved impact of vaccination on antimicrobial resistant infections, the relevance of indirect protection and the biological pressure induced by vaccination programs are examples of well-established vaccination topics that are commonly overlooked. A proper understanding of the effects of vaccination on unvaccinated groups through indirect or herd immunity is crucial, but this is frequently misinterpreted. Moreover, there is a growing distrust in vaccines and vaccination programs that needs to be addressed by researchers with appropriate technical skills. Thus, there is a growing global need for training in vaccinology and the study of vaccine-preventable diseases encompassing the entire process from vaccine development to field implementation and program evaluation. To address these needs, Vanderbilt University Medical Center (VUMC), the Instituto de Investigacion Nutricional (IIN) and the Universidad Peruana Cayetano Heredia (UPCH) are joining forces to build the Peru-Vanderbilt Prevention through Vaccination Training Program (PREVENT). The overall goal of PREVENT is to develop a cadre of researchers and educators equipped with modern knowledge and expertise to lead vaccine preventable diseases research and training in Peru and to encourage US-based researchers to engage in vaccination research in low- and middle-income country (LMICs). PREVENT builds on the very successful 14-year Research Partnership with the IIN and UPCH and on the Vanderbilt Vaccine Training and Evaluation Unit and the Division of Pharmacoepidemiology's expertise in the study of vaccine preventable diseases, training and mentoring. PREVENT will support 10 medium-long term trainees (Master's, PhD and faculty fellowships). Specifically, PREVENT aims to 1) Train a cadre of researchers and educators (trainers) to conduct multidisciplinary vaccine preventable diseases research and build training capacity in Peru; 2) Train scientists and future leaders in vaccine-preventable diseases research in Peru; and, 3) Ensure and document PREVENT's long-term impact. The ongoing IIN/UPCH-Vanderbilt Research Partnership has proven highly productive and successful. A new training program focusing on Vaccinology and the study of vaccine preventable diseases and the growth of structures and efforts to increase grant success will move IIN and UPCH toward a new horizon in vaccine preventable diseases and address Peru's need for a world-class workforce trained in vaccinology.

总结 虽然疫苗接种是发达国家和发展中国家预防传染病的最有效工具， 在发展中国家，实施有效的疫苗接种计划具有挑战性。开发、 有效疫苗接种的引进和实施取决于当地产生的证据的可用性， 特别是当地监管机构要求的数据。要做到这一点，一个基本要求是 拥有训练有素的当地研究人员，他们对疫苗背后的过程有着清晰的了解， 开发、疫苗引进和方案实施。培训研究人员， 疫苗接种对抗生素耐药性感染的影响，间接保护的相关性和生物学 疫苗接种计划引起的压力是公认的疫苗接种主题的例子， 常被忽视。通过以下方式正确了解疫苗接种对未接种疫苗群体的影响 间接或群体免疫至关重要，但这一点经常被误解。此外，人们越来越不信任 疫苗和疫苗接种计划需要研究人员通过适当的技术 skills.因此，全球对疫苗学培训和疫苗可预防疾病研究的需求日益增长。 涵盖从疫苗开发到现场实施和计划的整个过程 评价为了满足这些需求，范德比尔特大学医学中心（VUMC）， 营养调查（IIN）和秘鲁卡耶塔诺埃雷迪亚大学（UPCH）正在联手， 建立秘鲁-范德比尔特预防接种培训方案。的总目标 预防是培养一支拥有现代知识和专业知识的研究人员和教育工作者骨干队伍 在秘鲁领导疫苗可预防疾病的研究和培训，并鼓励美国研究人员 在低收入和中等收入国家开展疫苗接种研究。预防建立在 与IIN和UPCH以及范德比尔特疫苗培训的成功的14年研究伙伴关系， 评价单位和药物流行病学司在疫苗预防研究方面的专业知识 疾病、培训和指导。预防将支持10名中长期受训人员（硕士、博士和 教师奖学金）。具体而言，预防的目标是：1）培训一批研究人员和教育工作者（培训员）， 在秘鲁开展多学科疫苗可预防疾病研究并建立培训能力; 2）培训 秘鲁疫苗可预防疾病研究的科学家和未来领导者; 3）确保和记录 预防的长期影响。正在进行的IIN/UPCH-Vanderbilt研究伙伴关系已经证明了高度 富有成效和成功。一个新的培训计划，重点是疫苗学和疫苗研究 可预防的疾病和结构的增长以及提高赠款成功率的努力将推动IIN和 UPCH迈向疫苗可预防疾病的新视野，并满足秘鲁对世界级疫苗的需求。 受过疫苗学培训的劳动力。