DIETARY CALCIUM/BEHAVIORAL INTEVENTION IN CHILDREN WITH JRA

JRA 儿童的膳食钙/行为干预

• 批准号: 7374488
• 负责人: LORI J STARK
• 金额: $ 0.41万
• 依托单位: CINCINNATI CHILDRENS HOSP MED CTR
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-12-01 至 2006-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7374488
• 关键词: DIETARY; CALCIUM; BEHAVIORAL; INTEVENTION; CHILDREN

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Children with JRA are at risk for low bone mass and fracture in early adulthood. The present project compares a Behavior Intervention Program (BI) to an enhanced standard of care condition (ESC) for increasing dietary calcium intake and bone mass in children with JRA. The program evaluates dietary calcium intake pre to post intervention (approximately 8 weeks later) and at 6 month intervals over 2 years. Bone mass is also examined at baseline and at 6 month intervals for 2 years post treatment. It is hypothesized that children with JRA receiving the BI will have a significantly greater dietary calcium intake per day than children with JRA receiving ESC pre to post treatment (8 weeks). It is also hypothesized that the increased calcium intake of the BI group will be maintained across 24 months post treatment and that the calcium intake of the BI group will be significantly greater than the ESC group. Finally, it is hypothesized that the BI condition will result in a significantly greater increase in bone mass than the ESC.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。患有JRA的儿童在成年早期有低骨量和骨折的风险。本项目比较了行为干预计划（BI）和加强标准护理条件（ESC），以增加JRA儿童的膳食钙摄入量和骨量。该计划评估干预前后（约8周后）和2年内每隔6个月的膳食钙摄入量。还在基线和治疗后2年每6个月检查一次骨量。假设接受BI治疗的JRA儿童每日膳食钙摄入量显著高于治疗前至治疗后（8周）接受ESC治疗的JRA儿童。还假设BI组增加的钙摄入量将在治疗后24个月内维持，BI组的钙摄入量将显著高于ESC组。最后，假设BI条件导致的骨量增加显著大于ESC。