BEHAVIOR TREATMENT AND NUTRITION IN PEDIATRIC CHRONIC DISEASE

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 患有炎症性肠病(IBD；溃疡性结肠炎和克罗恩病)的儿童和青少年在成年早期就有骨量减少和骨折的风险。本项目比较了行为干预计划(BI)和标准护理条件(STC)，以增加IBD儿童的膳食钙摄入量和骨量。该计划在干预前和干预后(大约8周后)评估钙摄入量，并在两年内每隔6个月评估一次。治疗结束后2年内，每隔6个月进行一次基线骨量检查。据推测，接受BI治疗的IBD儿童每天的膳食钙摄入量将显著高于接受STC治疗的IBD儿童(8周)。还假设BI组增加的钙摄入量在治疗后24个月内保持不变，BI组的钙摄入量将显著高于STC组。最后，假设BI条件下骨量的增加明显大于STC。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Children and adolescents with inflammatory bowel disease (IBD; ulcerative colitis and Crohn's Disease) are at risk for low bone mass and fracture in early adulthood. The present project compares a Behavior Intervention Program (BI) to a standard of care condition (STC) for increasing dietary calcium intake and bone mass in children with IBD. The program evaluates calcium intake pre to post intervention (approximately 8 weeks later) and at 6 month intervals over 2 years. Bone mass will also be examined at baseline and at 6 month intervals for 2 years post treatment. It is hypothesized that children with IBD receiving the BI will have a significantly greater dietary calcium intake per day than children with IBD receiving STC pre to post treatment (8 weeks). It is also hypothesized that the increased calcium intake of the BI group will be maintained across 24 months post treatment and that the calcium intake of the BI group will be significantly greater than the STC group. Finally, it is hypothesized that the BI condition will result in a significantly greater increase in bone mass than the STC.