General Clinical Research Center

超出空间 但前提是。 科罗拉多大学医学院儿科综合临床研究中心(GCRC)的延续 丹佛医学和儿童医院的目的是提供设施和 支持多学科住院和门诊健康和健康临床调查的基础设施 婴儿、儿童和青少年的疾病。这份续签建议书包括95个GCRC咨询 委员会批准的个人临床研究项目，已由初级和高级提交 来自医学院、护理和药学学院基础和临床部门的调查人员，大多数 他们得到同行审查的独立赠款资金的支持。感兴趣的主要研究课题包括 低出生体重儿和足月儿营养与氨基酸代谢，吸入一氧化氮治疗； 预防和治疗I型和II型糖尿病、乳糜泻、囊性纤维化、传染性疾病 肺部疾病、多囊肾病、胆道闭锁等慢性肝病、镰状细胞 疾病、青少年怀孕、艾滋病毒感染和微量营养素代谢。儿科GCRC设施 需要支持的包括六个床位的住院部、门诊部、围产期和儿科、 分散服务，一个核心和分子核心实验室，一个生物营养学核心，一个生物统计学核心， (生物)信息学核心、研究主题倡导者计划和管理核心。GCRC将 还培养和参与了年轻临床研究人员的培训。在这项提案的第二年，GCRC 将搬迁到新儿童医院的扩建设施，该医院正在建设中的菲茨西蒙斯校园 科罗拉多大学健康科学中心(UCSHC)。南加州大学校区的新地点将会有所帮助 促进进一步的跨学科研究和更多的合作。The Program-DirectorwilJ继续 鼓励和便利UCHSG的其他独立资助的调查人员研究儿童时期的Jieajth：，. 以及研究实习生，以参与儿科GCRC。，，r，..。

EXCEED THE SPACE PROVIDED. Continuation of the Pediatric General Clinical Research Center (GCRC) at the University of Colorado School of Medicine and The Children's Hospital of Denver is proposed for the purpose of providing facilities and infrastructure to support multi-disciplinary inpatient and outpatient clinical investigation of health and diseases of infants, children, and adolescents. This renewal proposal includes 95 GCRC Advisory Committee-approved individual clinical research projects that have been submitted by both junior and senior investigators from basic and clinical departments of the Schools of Medicine, Nursing and Pharmacy, most of whom are supported by peer-reviewed independent grant funding. Major research topics of interest include nutrition and amino acid metabolism in low birth weight and term infants, inhaled nitric oxide therapy; prevention and treatment of types I and II diabetes mellitus, celiac disease, cystic fibrosis, infectious pulmonary diseases, polycystic kidney disease, biliary atresia and other chronic liver diseases, sickle cell disease, adolescent pregnancy, HIV infection, and micronutrient metabolism. The Pediatric GCRC facilities for which support is requested include a six-bed Inpatient Unit, an Outpatient Unit, Perinatal and Pediatric,, Scatterbed services, a Core and Molecular Core Laboratory, a Bionutrition Core, a Biostatistics Core, a ,; (Bio)lnformatics Core, a Research Subject Advocate Program, and an Administrative Core. The GCRC will also foster and participate in the training of young clinical investigators. In year 2 of this proposal, the GCRC will relocate to expanded facilities at the new Children's Hospital being built on the Fitzsimons campus of the University of Colorado Health Sciences Center (UCSHC). The new location on the UCHSC campus will help stimulate further interdisciplinary research and increased collaboration. The Program-DirectorwilJ continue to encourage and facilitate other independently-funded investigators at UCHSG studying childhoodJieajth:,., and illness, as well as research trainees, to become involved in the Pediatric GCRC. , ,r ,.., .,..,.