CL CHANNEL ACTIVITY AND FUNCTION IN SYSTEMIC SCLEROSIS MYOFIBROBLASTS

系统性硬化症肌成纤维细胞中 CL 通道的活性和功能

• 批准号: 7375445
• 负责人: ARNOLD E POSTLETHWAITE
• 金额: $ 0.52万
• 依托单位: UNIVERSITY OF TENNESSEE HEALTH SCI CTR
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-12-01 至 2006-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7375445
• 关键词: CL; CHANNEL; ACTIVITY; FUNCTION; SYSTEMIC

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study is designed to examine the ion channel in cells in blood and skin from patients with scleroderma, to compare the channel's activity with cells from healthy controls and to see if blocking the channel's activity can prevent the formation of myofibroblasts.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。这项研究旨在检查硬皮病患者血液和皮肤细胞中的离子通道，将通道的活性与健康对照细胞进行比较，并观察阻断通道的活性是否可以防止肌成纤维细胞的形成。