BEDREST AND AGING: PROJECT 2 EXERCISE AND MUSCLE

卧床休息和衰老：项目 2 锻炼和肌肉

• 批准号: 7377685
• 负责人: W. DOUGLAS EVANS
• 金额: $ 9.07万
• 依托单位: UNIV OF ARKANSAS FOR MED SCIS
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-01 至 2007-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7377685
• 关键词: BEDREST; AGING; PROJECT; EXERCISE; MUSCLE

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We will test the following hypotheses in a group of older men and women (6580 years) who will undergo 10 days of bedrest only, bedrest with therapeutic resistance exercise, or bedrest with standard-of-care walking exercise. Resistance exercise will consist of training the knee extensor and flexor muscles every third day (three sets of eight repetitions at 80% of the one-repetition maximum [1RM]). Standard-of-care walking exercise will consist of 15 minutes of walking every day.

该子项目是利用 NIH/NCRR 资助的中心拨款提供的资源的众多研究子项目之一。子项目和研究者 (PI) 可能已从另一个 NIH 来源获得主要资金，因此可以在其他 CRISP 条目中得到体现。列出的机构是中心的机构，不一定是研究者的机构。我们将在一组老年男性和女性（6580 岁）中测试以下假设，他们将仅卧床休息 10 天、卧床休息并进行治疗性阻力运动、或卧床休息并进行标准护理步行运动。抗阻训练包括每三天训练一次膝关节伸肌和屈肌（三组，每组八次，重复次数为单次最大重复次数的 80% [1RM]）。标准步行锻炼包括每天步行 15 分钟。