IMPROVING ORTHOSTATIC TOL IN WOMEN: CONTROL OF SPLANCHNIC & CUTANEOUS VAS CAPAC

改善女性的直立性疲劳：控制内脏

• 批准号: 7378524
• 负责人: James A Pawelczyk
• 金额: $ 3.01万
• 依托单位: PENNSYLVANIA STATE UNIV HERSHEY MED CTR
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-01 至 2007-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7378524
• 关键词: IMPROVING; ORTHOSTATIC; TOL; WOMEN; CONTROL

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This proposal seeks to utilize pharmacological countermeasures to improve orthostatic tolerance in women. We postulate that an infusion of octreotide prior to head-up tilt (HUT) will decrease splanchnic blood flow, causing a redistribution of blood to other regions of the body and thus will improve orthostatic tolerance.

该子项目是利用 NIH/NCRR 资助的中心拨款提供的资源的众多研究子项目之一。子项目和研究者 (PI) 可能已从另一个 NIH 来源获得主要资金，因此可以在其他 CRISP 条目中得到体现。列出的机构是中心的机构，不一定是研究者的机构。该提案旨在利用药理学对策来提高女性的直立耐受性。 我们假设在抬头倾斜（HUT）之前输注奥曲肽会减少内脏血流量，导致血液重新分配到身体的其他区域，从而提高直立耐受性。