Planning Grant for CTSA at MUSC

描述(由申请者提供)：这项建议侧重于规划过程，以发展临床和翻译科学作为一门学科的学术之家，并改变临床和翻译研究人员在南卡罗来纳医科大学(MUSC)培训和支持的方式。MUSC目前拥有一系列不同的临床和转化研究活动，包括由NIH资助的GCRC和跨学科路线图T32计划。规划活动将汇集来自MUSC和该州其他机构的具有丰富的临床、基础科学、行政和社区推广专业知识的个人。MUSC的最高领导层将全面参与，以及来自全州的政治和商业领导人。规划活动将由两名内科科学家共同指导，他们是公认的翻译研究人员和模范导师。监督和整合将由一个机构规划委员会提供，该委员会由具有经验、热情和权威的研究人员和行政领导人组成，以确定优先事项并实施必要的变革，以改变文化和基础设施，以实现总体目标。规划期分为3个阶段，历时18个月(需求评估、计划整合和实施)。该大学已承诺提供机构资金，以支持潜在获奖日期之前的规划活动，并在预期获奖期间提供补充支持。将使用以下方法-分析战略优势、劣势、机会和威胁(SWOT)；将在12个重点领域进行需求评估并制定具体建议的工作组；组织规划和变革管理方面的专业咨询公司的专家咨询，以及处于临床和转化性研究开发和实施更高级水平的其他组织的临床和转化性研究方面的学术/科学领袖。这项建议的具体目的是：(1)确定MUSC的CTSA的最佳结构和基础设施；(2)评估对于发展和维持临床和转化性研究作为一门学科并在MUSC拥有真正的学术基础的关键资源和需求；(3)设计新的计划或服务，以满足规划过程中确定的关键需求，(4)整合现有资源，以加强MUSC以及我们在本地、全州和全国范围内与之合作的机构、机构和临床网络的临床和转译活动。规划进程的一个里程碑是提交一份具有竞争力的CTSA U54提案。我们的计划包括旨在促进和评估持续的文化和组织变革的评估。该战略计划的制定和后续实施将有可能改变MUSC的研究企业和国家。

DESCRIPTION (provided by applicant): This proposal focuses on a planning process to develop an academic home for clinical and translational science as a discipline and transform the way in which clinical and translational researchers are trained and supported at the Medical University of South Carolina (MUSC). MUSC currently has a diverse portfolio of clinical and translational research activities, including an NIH-funded GCRC and interdisciplinary Roadmap T32 Program. The planning activities will bring together individuals with substantial clinical, basic science, administrative and community outreach expertise from MUSC and other institutions in the state. The highest level of MUSC leadership will be integrally involved as well as political and business leaders from throughout the state. The planning activities will be co-directed by two physician-scientists who are well-established translational researchers and exemplary mentors. Oversight and integration will be provided by an Institutional Planning Committee composed of researchers and administrative leaders with the experience, enthusiasm and authority to prioritize and implement the changes needed to transform the culture and infrastructure to achieve the overall objective. The planning period has 3 phases spanning 18 months (needs assessment, plan integration, and implementation). The university has committed institutional funds to support planning activities prior to the potential award date, and for supplemental support during the anticipated award period. The following approaches will be utilized-analysis of strategic strengths, weakness, opportunities, and threats (SWOT); work groups who will conduct a needs assessment and develop concrete recommendations in 12 focal areas; and expert consultation from a professional consulting firm in organization planning and change management as well as academic/scientific leaders in clinical and translational research from other organizations that are at amore advanced level of clinical and translational research development and implementation. The specific aims of this proposal are to: (1) Identify the optimal structure and infrastructure for the CTSA at MUSC; (2)Assess resources and needs that are critical to develop and sustain clinical and translational research as a discipline with a true academic home at MUSC; (3) Design new programs or services to address critical needs identified in the planning process, (4) Integrate existing resources to enhance the clinical and translational activities of MUSC and the institutions, agencies and clinical networks with which we collaborate locally, statewide, and nationally. A milestone of the planning process is submission of a competitive CTSA U54 proposal. Our plan includes assessments designed to facilitate and evaluate cultural and organizational change on an ongoing basis. The development and subsequent implementation of the strategic plan has the potential to transform the research enterprise of MUSC and the state.