Risk Perception/Communications/Reduction Behaviors

风险认知/沟通/减少行为

• 批准号: 7437380
• 负责人: LOIS J LOESCHER
• 金额: $ 13.14万
• 依托单位: UNIVERSITY OF ARIZONA
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-06-01 至 2010-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7437380
• 关键词: Academic Career Award; Accounting; Address; Affect; Area; Arizona; Awareness; Behavior; Behavior Control; Behavior Therapy; Behavioral; Behavioral Model; Breast; Cancer Center; Cancer Cluster; Cancer Prevention, Control and Population Sciences Career Development Award (K07); Cardiac; Categories; Characteristics; Chemoprevention; Clinical; Clinical Nursing; Clinical Trials; Code; Collaborations; Colonic Adenoma; Colonic Polyps; Colorectal Cancer; Communication; Communication Research; Communities; Comprehensive Cancer Center; Condition; Data; Development; Disease; Doctor of Medicine; Doctor of Philosophy; Dysplastic Nevus; Exhibits; Faculty; Family; Family member; First Degree Relative; Foundations; Future; Gene Mutation; Genes; Genetic; Genetic Counseling; Genetic Predisposition to Disease; Genetic Risk; Genetic screening method; Germ Lines; Goals; Health Personnel; Health behavior; Hereditary Disease; Hereditary Malignant Neoplasm; Hereditary Melanoma; Hereditary Neoplastic Syndromes; Incidence; Individual; Inheritance Patterns; Inherited; International; Interview; Knowledge; Location; Malignant Neoplasms; Malignant neoplasm of ovary; Measures; Melanocytic nevus; Mentors; Methods; Modeling; Mole the mammal; Monitor; Mutation; Nature; Newly Diagnosed; Obesity; Ovarian; Patients; Perception; Persons; Phase; Population; Population Research; Precancerous Conditions; Premalignant; Prevention Research; Primary Health Care; Process; Property; Psychometrics; Publishing; Registered nurse; Relative (related person); Reporting; Research; Research Personnel; Risk; Risk Reduction; Risk Reduction Behavior; Screening procedure; Shapes; Site; Skin Cancer; Testing; Title; Training; Universities; Woman; autosomal dominant trait; base; behavioral clinical trial; cancer genetics; cancer prevention; cancer risk; communication theory; experience; family influence; instrument; knowledge base; melanoma; men; mortality; post-doctoral training; programs; response; theories; tumor

DESCRIPTION (provided by applicant): Lois J. Loescher, Ph.D., R.N., is a junior investigator involved in cancer genetic risk research at the Arizona Cancer Center (AZCC). A 5-year K07 award will prepare her as an independent investigator to conduct theory-based, behavioral clinical trials with the ultimate goal to decrease cancer incidence/mortality in individuals and families at genetic risk for cancer. Dr. Loescher's previous training in nursing and clinical genetics and her postdoctoral training in psychometric analysis support her ability to move forward from descriptive theory testing to behavioral intervention clinical trials models. The formal training she now needs will target health behavior theories, intrafamily communications theories/models, multi-method analytic approaches (qualitative and quantitative), and will enable her to conduct behavioral trials within cancer-prone families. Dr. Loescher's training will occur at the University of Arizona and several U.S. locations. The AZCC is an NCI-designated comprehensive cancer center with an international reputation for cancer prevention research. Dr. Loescher's sponsors are David S. Alberts, M.D. (AZCC) and Nell D. Weinstein, Ph.D. (Rutgers University) who will mentor her in skin cancer prevention research/clinical trials development and risk perception/communication research, respectively. Additional collaborations with other faculty experts in the targeted training areas provide the intellectual foundation for the K07 experience. Dr. Loescher's research plan focuses on melanoma-prone families and builds on current research programs at the AZCC. No published studies address specific risk processes (defined as perceived risk, intrafamily risk communications, health-care-provider originated risk communications, and risk control actions) in melanoma-prone families. Phase 1 seeks to describe, analyze, and interpret family members' risk processes; and develop a multidimensional instrument to measure of melanoma risk communications. Phase 1 will use rigorously coded qualitative interview data to elicit information about domains of risk communications that can be incorporated into the proposed instrument and used for future behavioral models. Specific aims of Phase 2 are to assess the psychometric properties of measures of melanoma risk processes (defined above) and a related construct, cancer worry. Additionally the relationships of risk process variables and cancer worry will be evaluated in at least 240 patients with melanoma or dysplastic nevi and their first-degree relatives (FDRs). Phase 2 will evaluate differences in risk control behaviors between melanoma/DN patients and FDRs. Results of this research will be used to formulate a model of risk processes and develop future behavioral interventions to reduce cancer risk.

描述（由申请人提供）：Lois J. Loescher，Ph.D.，R.N.：是亚利桑那州癌症中心（AZCC）癌症遗传风险研究的初级研究员。 一个为期5年的K 07奖将准备她作为一个独立的研究者进行基于理论的，行为的临床试验，最终目标是降低癌症遗传风险的个人和家庭的癌症发病率/死亡率。 Loescher博士以前在护理和临床遗传学方面的培训以及她在心理测量分析方面的博士后培训支持她从描述性理论测试到行为干预临床试验模型的能力。 她现在需要的正式培训将针对健康行为理论，家庭内部沟通理论/模型，多方法分析方法（定性和定量），并将使她能够在癌症易感家庭中进行行为试验。Loescher博士的培训将在亚利桑那大学和美国的几个地点进行。 AZCC是一个NCI指定的综合性癌症中心，在癌症预防研究方面享有国际声誉。 勒舍尔医生的赞助人是大卫S. Alberts，医学博士（AZCC）和Nell D.温斯坦博士 （罗格斯大学）谁将指导她在皮肤癌预防研究/临床试验开发和风险认知/沟通研究。 在目标培训领域与其他教师专家的额外合作为K 07的经验提供了知识基础。 Loescher博士的研究计划侧重于黑色素瘤易感家庭，并建立在AZCC目前的研究项目基础上。 没有发表的研究涉及黑色素瘤易感家庭的特定风险过程（定义为感知风险，家庭内风险沟通，医疗保健提供者发起的风险沟通和风险控制行动）。 第一阶段旨在描述，分析和解释家庭成员的风险过程;并开发一种多维工具来衡量黑色素瘤风险沟通。 第一阶段将使用严格编码的定性访谈数据，以获取有关风险沟通领域的信息，这些信息可以纳入拟议的工具中，并用于未来的行为模型。 第2阶段的具体目标是评估黑色素瘤风险过程（如上所述）和相关结构（癌症担忧）的心理测量特性。 此外，将在至少240例黑色素瘤或发育不良痣患者及其一级亲属（FDR）中评估风险过程变量与癌症担忧的关系。 第2阶段将评估黑色素瘤/DN患者和FDR之间风险控制行为的差异。 这项研究的结果将用于制定风险过程模型并开发未来的行为干预措施以降低癌症风险。

项目成果

Perceived intrafamily melanoma risk communication.

• DOI: 10.1097/ncc.0b013e31819ae11c
• 发表时间: 2009-05
• 期刊: Cancer nursing
• 影响因子: 2.6
• 作者: Loescher LJ;Crist JD;Siaki LA
• 通讯作者: Siaki LA

Pacific Islanders' perceived risk of cardiovascular disease and diabetes.

太平洋岛民感知的心血管疾病和糖尿病风险。

• DOI: 10.1177/1043659610395763
• 发表时间: 2011
• 期刊: Journal of transcultural nursing : official journal of the Transcultural Nursing Society
• 作者: Siaki,LeilaniA;Loescher,LoisJ
• 通讯作者: Loescher,LoisJ

Use of technology for educating melanoma patients.

• DOI: 10.1007/s13187-010-0072-3
• 发表时间: 2010-09
• 期刊: Journal of cancer education : the official journal of the American Association for Cancer Education
• 作者: Marble N;Loescher LJ;Lim KH;Hiscox H
• 通讯作者: Hiscox H

Melanoma high-risk families' perceived health care provider risk communication.

• DOI: 10.1080/08858190902997290
• 发表时间: 2009
• 期刊: Journal of cancer education : the official journal of the American Association for Cancer Education
• 作者: Loescher LJ;Crist JD;Cranmer L;Curiel-Lewandrowski C;Warneke JA
• 通讯作者: Warneke JA

A cultural perspective of Samoans' perceived risk of cardiovascular disease and diabetes.

从文化角度看待萨摩亚人心血管疾病和糖尿病的认知风险。

• DOI: 10.1097/jcn.0b013e31822b9be3
• 发表时间: 2012
• 期刊: The Journal of cardiovascular nursing
• 作者: Siaki,LeilaniA;Loescher,LoisJ;Ritter,Leslie
• 通讯作者: Ritter,Leslie