NEURODEVELOPMENT

神经发育

• 批准号: 7609614
• 负责人: D CHRISTIAN DERAUF
• 金额: $ 7.84万
• 依托单位: UNIVERSITY OF HAWAII AT MANOA
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-07-01 至 2008-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7609614
• 关键词: 3 year old; Age-Years; Anatomy; Arousal; Attention; Biochemical; Child; Child Behavior; Cognitive; Computer Retrieval of Information on Scientific Projects Database; Development; Disease; Funding; Grant; Human; Informal Social Control; Institution; Measurable; Memory; Metabolic; Metabolism; Nervous system structure; Nursery Schools; Purpose; Research; Research Personnel; Resources; Source; Structure; United States National Institutes of Health; fetal methamphetamine exposure; neurodevelopment

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of the proposed research is to study the potential anatomic and metabolic changes in the developing human nervous system associated with prenatal methamphetamine (MA) exposure, and the relationship of these changes to measurable alterations in child behavior and development in the preschool period. Preliminary studies suggest that prenatal MA exposure is associated with alterations in the volume and biochemical composition of specific CNS regions, and with disordered attention and verbal memory. The specific aims of the proposal are: (1) to identify the effects of prenatal MA exposure on CNS structure and metabolism in three-year-old children, and (2) to examine the relationship between prenatal MA exposure, CNS structure and metabolism, and two cognitive domains, attention and arousal/self-regulation, assessed at 2 and 3 years of age.

这个子项目是众多研究子项目之一