PREPARATION, DERIVATIZATION &: NANOSTRUCTURED MATERIALS

制备、衍生化

• 批准号: 7355190
• 负责人: Karen L. Wooley
• 金额: $ 0.12万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-02-01 至 2007-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7355190
• 关键词: PREPARATION; DERIVATIZATION; NANOSTRUCTURED; MATERIALS

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The self-assembly and covalent stabilization of amphiphilic block copolymers is being developed as a methodology for the preparation of robust nanostructured materials of well-defined structure, composition, and size, which are designed for specific materials properties and to exhibit selective biological interactions. MALDI-TOF has been a critical characterization tool for the characterization of the amphiphilic block copolymers. Mass spectrometric analysis has also played a significant role in the characterization of molecular components, e.g. antibiotics, peptides, sugars, etc., used to surface decorate the nanostructures.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心机构，不一定为研究者机构。两亲性嵌段共聚物的自组装和共价稳定化正被开发为用于制备具有明确定义的结构、组成和尺寸的稳健纳米结构材料的方法，所述纳米结构材料被设计用于特定的材料性质并表现出选择性的生物相互作用。MALDI-TOF已成为表征两亲嵌段共聚物的重要表征工具。质谱分析在分子组分（例如抗生素、肽、糖等）的表征中也发挥了重要作用，用于表面修饰纳米结构。