Characterization Of Perpetrators Of Domestic Violence
家庭暴力施暴者的特征
基本信息
- 批准号:6983065
- 负责人:
- 金额:--
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:
- 资助国家:美国
- 起止时间:至
- 项目状态:未结题
- 来源:
- 关键词:aggressionalcoholism /alcohol abusebehavioral /social science research tagbioimaging /biomedical imagingbrain imaging /visualization /scanningbrain mappingcentral neural pathway /tractclinical researchdisease /disorder etiologydomestic violencefearhuman subjectmental disorder diagnosispositron emission tomographypsychobiologypsychopathologypsychopharmacologyself destructive behaviorspouse abuseviolence
项目摘要
Domestic violence is a problem of major proportions in the United States. The majority of studies pertaining to the etiology of domestic violence have focused on psychosocial parameters with little emphasis on biological factors.
We analyzed data obtained from PET imagining and found that perpetrators of domestic violence have decreased glucose metabolism in the hypothalamus compared to controls. Perpetrators also showed decreased correlations in glucose metabolism between several cortical and subcortical structures and the amygdala. This published data provides the basis for us to integrate the behaviors and psychiatric diagnoses of perpetrators of domestic violence with abnormalities in the structures and pathways that control the expression of fear-induced aggression.
Currently, we have sent a manuscript for review and publication proposing a model which attributes many of the behaviors demonstrated by perpetrators of domestic violence as being conditioned fear responses (i.e., fight, flight, shutdown) or conditioned fear avoidant responses (i.e., alcohol consumption, self-injurious behaviors). It is our goal that this model will form the basis for future research in order to better understand and to treat perpetrators of domestic violence.
家庭暴力在美国是一个严重的问题。大多数关于家庭暴力病因的研究都集中在社会心理因素上,很少强调生物学因素。
项目成果
期刊论文数量(0)
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科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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David T George其他文献
The CRF1 Antagonist Verucerfont in Anxious Alcohol-Dependent Women: Translation of Neuroendocrine, But not of Anti-Craving Effects
焦虑型酒精依赖女性中的 CRF1 拮抗剂 Verucerfont:神经内分泌的翻译,但不是抗渴望效应的翻译
- DOI:
10.1038/npp.2016.61 - 发表时间:
2016-04-25 - 期刊:
- 影响因子:7.100
- 作者:
Melanie L Schwandt;Carlos R Cortes;Laura E Kwako;David T George;Reza Momenan;Rajita Sinha;Dimitri E Grigoriadis;Emilio Merlo Pich;Lorenzo Leggio;Markus Heilig - 通讯作者:
Markus Heilig
David T George的其他文献
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{{ truncateString('David T George', 18)}}的其他基金
Assessment,Treatment, and Pharmacological Interventions in Alcoholic Patients
酗酒患者的评估、治疗和药理学干预
- 批准号:
8156730 - 财政年份:
- 资助金额:
-- - 项目类别:
Clinical trial of SR141716, Rimonabant, to reduce volunt
SR141716、利莫那班的临床试验,以减少自愿
- 批准号:
6983095 - 财政年份:
- 资助金额:
-- - 项目类别:
YOHIMBINE CHALLENGE TO STUDY NORADRENERGIC FUNCTION IN INDIVIDUALS
育亨宾挑战研究个体去甲肾上腺素能功能
- 批准号:
6097574 - 财政年份:
- 资助金额:
-- - 项目类别:
NK1 receptor antagonism for treatment of alcohol-dependent patients
NK1受体拮抗剂治疗酒精依赖患者
- 批准号:
7732104 - 财政年份:
- 资助金额:
-- - 项目类别:
Clinical Assessment and Treatment Evaluation of Alcohol Dependent Patients
酒精依赖患者的临床评估和治疗评价
- 批准号:
7963833 - 财政年份:
- 资助金额:
-- - 项目类别:
SR141716, Rimonabant, to reduce alcohol consumption
SR141716,利莫那班,减少酒精消耗
- 批准号:
7146650 - 财政年份:
- 资助金额:
-- - 项目类别: