A Miniature Monitor for Time-Resolved Airborne Particle Chemistry

时间分辨空气颗粒化学的微型监测仪

• 批准号: 7482003
• 负责人: Susanne Vera Hering
• 金额: $ 38.22万
• 依托单位: AEROSOL DYNAMICS, INC.
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-16 至 2010-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7482003
• 关键词: Address; Aerosols; Alcohols; Aromatic Polycyclic Hydrocarbons; Biological Assay; Caliber; Cardiovascular system; Chemicals; Chemistry; Class; Collection; Date/Time; Deposition; Detection; Development; Drops; Equipment; Evaluation; Exposure to; Goals; Health; Individual; Ions; Knowledge; Laboratories; Liquid Chromatography; Liquid substance; Location; Measurement; Measures; Methodology; Methods; Modeling; Monitor; Numbers; Operative Surgical Procedures; Particulate; Particulate Matter; Phase; Physical condensation; Poison; Public Health; Pump; Range; Research; Resolution; Sampling; Source; Standards of Weights and Measures; Steam; System; Techniques; Technology; Time; Validation; Water; Weight; Work; airborne allergen; ambient particle; ammonium nitrate; base; cost; design; detector; environmental agent; exposed human population; improved; light scattering; miniaturize; novel; particle; particle counter; pressure; respiratory; sample collection; size; tool; water flow

DESCRIPTION (provided by applicant A miniature, battery-powered monitor will be developed for measurement of hourly concentrations of chemical constituents of PM2.5 aerosols that are important to human exposure. The method utilizes a laminar-flow, water condensation method to provide a concentrated, "ready-to-analyze" deposit of ambient particles. Many deposits will be contained on a single collection wafer designed for automatic analysis by common liquid chromatographic methods. The objective is wide-scale, inexpensive time-resolved monitoring of individual constituents of ambient particulate matter for personal exposures assessment. PUBLIC HEALTH RELEVANCE: Proposed is the development of a compact, battery powered monitor to provide time-resolved measurements of personal exposures to many of the toxic chemical components of PM2.5. Short- term exposures to high levels may be important for understand the respiratory and cardiovascular health effects of exposure. This research improves the time-resolution and the range of chemical components that can be measured in personal monitoring studies.

描述（由申请人提供）将开发一种微型电池供电监测仪，用于测量PM2.5气溶胶中对人体暴露很重要的化学成分的每小时浓度。该方法利用层流、水冷凝的方法来提供浓缩的、“随时可分析”的环境颗粒沉积物。许多沉积物将包含在一个收集晶片上，设计用于普通液相色谱方法的自动分析。目标是对环境颗粒物的单个成分进行大规模、廉价的时间分辨监测，以进行个人暴露评估。公共卫生相关性：建议开发一种紧凑的电池供电监测仪，以提供个人暴露于PM2.5中许多有毒化学成分的时间分辨率测量。短期暴露于高水平可能对了解暴露对呼吸和心血管健康的影响很重要。本研究提高了个人监测研究中可测量的化学成分的时间分辨率和范围。