HEREDITARY ENDOCRINE CANCER: A MODEL BASED ON PHAEOCHROMOCYTOMA- PARAGANGLIOMA SYNDROMES

遗传性内分泌癌:基于嗜铬细胞瘤-副神经节瘤综合征的模型

基本信息

  • 批准号:
    nhmrc : GNT1108032
  • 负责人:
  • 金额:
    $ 87.59万
  • 依托单位:
  • 依托单位国家:
    澳大利亚
  • 项目类别:
    Project Grants
  • 财政年份:
    2016
  • 资助国家:
    澳大利亚
  • 起止时间:
    2016-01-01 至 无数据
  • 项目状态:
    已结题

项目摘要

Phaeochromocytomas and paragangliomas are tumours remarkable for their very high heritability. They have a high burden of disease themselves, and their associated hereditary syndromes include risks for other malignancies. Our study will rationalize the pathological approach to diagnosing these hereditary syndromes, find new therapeutic targets for metastatic disease, and provide a template for other cancers with high heritable component.
嗜铬细胞瘤和副神经节瘤是具有很高遗传性的肿瘤。他们本身有很高的疾病负担,其相关的遗传综合征包括其他恶性肿瘤的风险。我们的研究将使诊断这些遗传综合征的病理方法合理化,为转移性疾病找到新的治疗靶点,并为其他具有高遗传成分的癌症提供模板。

项目成果

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A/Pr Alison Trainer其他文献

A/Pr Alison Trainer的其他文献

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{{ truncateString('A/Pr Alison Trainer', 18)}}的其他基金

Population based genetic testing for high-risk breast and ovarian cancer predisposition genes
基于人群的高风险乳腺癌和卵巢癌易感基因基因检测
  • 批准号:
    nhmrc : 1126679
  • 财政年份:
    2017
  • 资助金额:
    $ 87.59万
  • 项目类别:
    Project Grants
Population based genetic testing for high-risk breast and ovarian cancer predisposition genes
基于人群的高风险乳腺癌和卵巢癌易感基因基因检测
  • 批准号:
    nhmrc : GNT1126679
  • 财政年份:
    2017
  • 资助金额:
    $ 87.59万
  • 项目类别:
    Project Grants
HEREDITARY ENDOCRINE CANCER: A MODEL BASED ON PHAEOCHROMOCYTOMA- PARAGANGLIOMA SYNDROMES
遗传性内分泌癌:基于嗜铬细胞瘤-副神经节瘤综合征的模型
  • 批准号:
    nhmrc : 1108032
  • 财政年份:
    2016
  • 资助金额:
    $ 87.59万
  • 项目类别:
    Project Grants
iPrevent: Development and pilot testing of an evidence-based, tailored, computerised risk assessment and decision support tool to facilitate discussions about breast cancer prevention and screening measures.
iPrevent:开发和试点测试基于证据的、定制的、计算机化的风险评估和决策支持工具,以促进有关乳腺癌预防和筛查措施的讨论。
  • 批准号:
    nhmrc : 1064244
  • 财政年份:
    2014
  • 资助金额:
    $ 87.59万
  • 项目类别:
    Project Grants
Identification of novel genes predisposing to male breast cancer, their prevalence and associated cancer risks.
鉴定易患男性乳腺癌的新基因、其患病率和相关癌症风险。
  • 批准号:
    nhmrc : 1026840
  • 财政年份:
    2013
  • 资助金额:
    $ 87.59万
  • 项目类别:
    Project Grants
Identification of novel genes predisposing to familial colorectal cancer by full exome sequencing
通过全外显子组测序鉴定易患家族性结直肠癌的新基因
  • 批准号:
    nhmrc : 1028374
  • 财政年份:
    2013
  • 资助金额:
    $ 87.59万
  • 项目类别:
    Project Grants

相似海外基金

Role of P4HA1 in Endocrine Resistance of Breast Cancer
P4HA1在乳腺癌内分泌抵抗中的作用
  • 批准号:
    10571404
  • 财政年份:
    2023
  • 资助金额:
    $ 87.59万
  • 项目类别:
Analysis of cell-free DNA targeted sequence to develop of novel strategies for endocrine therapy-resistant breast cancer
分析游离 DNA 靶向序列以开发治疗内分泌治疗耐药乳腺癌的新策略
  • 批准号:
    23K06699
  • 财政年份:
    2023
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Beyond Cardiotoxicity: Characterizing the Short and Long-term Cardiovascular Side Effects of Breast Cancer Endocrine Treatment
超越心脏毒性:描述乳腺癌内分泌治疗的短期和长期心血管副作用
  • 批准号:
    488204
  • 财政年份:
    2023
  • 资助金额:
    $ 87.59万
  • 项目类别:
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Development and validation of innovative cellular models to predict breast cancer risks associated with endocrine disruptors such as PBDEs and their successors
开发和验证创新细胞模型,以预测与内分泌干扰物(如 PBDE 及其后继者)相关的乳腺癌风险
  • 批准号:
    491637
  • 财政年份:
    2023
  • 资助金额:
    $ 87.59万
  • 项目类别:
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Development of new endocrine therapy based on genomic classification for endometrial cancer
基于子宫内膜癌基因组分类开发新内分泌疗法
  • 批准号:
    23K15818
  • 财政年份:
    2023
  • 资助金额:
    $ 87.59万
  • 项目类别:
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Repurposing RET Inhibitors for Endocrine Resistant Breast Cancer
重新利用 RET 抑制剂治疗内分泌耐药乳腺癌
  • 批准号:
    10644068
  • 财政年份:
    2023
  • 资助金额:
    $ 87.59万
  • 项目类别:
Developing a culturally tailored mHealth symptom monitoring intervention to improve adherence to endocrine therapy among Black women with breast cancer
开发适合文化的移动健康症状监测干预措施,以提高患有乳腺癌的黑人女性对内分泌治疗的依从性
  • 批准号:
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  • 财政年份:
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Three-dimensional remnant pancreatic volume indicates postoperative pancreatic endocrine or exocrine insufficiency in pancreatic cancer patients after pancreatectomy
三维残余胰腺体积提示胰腺癌患者胰腺切除术后胰腺内分泌或外分泌不足
  • 批准号:
    23K19551
  • 财政年份:
    2023
  • 资助金额:
    $ 87.59万
  • 项目类别:
    Grant-in-Aid for Research Activity Start-up
Targeting secreted factors in endocrine resistant breast cancer therapy
内分泌耐药乳腺癌治疗中的靶向分泌因子
  • 批准号:
    10654343
  • 财政年份:
    2023
  • 资助金额:
    $ 87.59万
  • 项目类别:
Feasibility of Implementing Acupuncture into a Federally Qualified Health Center to Alleviate Multiple Symptoms Among Breast Cancer Survivors Receiving Endocrine therapy
在联邦合格的健康中心实施针灸以减轻接受内分泌治疗的乳腺癌幸存者的多种症状的可行性
  • 批准号:
    10510356
  • 财政年份:
    2022
  • 资助金额:
    $ 87.59万
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