7T Translational MRI System

7T平移磁共振成像系统

• 批准号: 7217821
• 负责人: A. Gregory Sorensen
• 金额: $ 50万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-05-01 至 2009-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7217821
• 关键词: Animal Model; Animals; Arts; Clinical; Computers; Development; Devices; Equipment; Funding; Human; Image; Magnetic Resonance Imaging; Medical; Performance; Physiologic pulse; Pulse taking; RF coil; Research; Research Personnel; Rodent; Solutions; Speed; System; Training; Translating; Work; bioimaging; design; insight; instrument; instrumentation; skills

DESCRIPTION (provided by applicant): We seek funding for a 7 Tesla translational MRI unit: a small animal system (7T / 30cm) with a clinical console. This off-the-shelf device will allow many users to translate between human and animal imaging by providing the same interface for both. The system is provided by Siemens Medical Solutions and Bruker, and matches the computers, RF system, and user interface of the human equipment currently in use at our center. The proposed system will have many additional features that make it a state-of-the-art instrument, including 32 RF receiver channels, multiple advanced pulse sequences, tailored RF coils for rodent imaging, and strong gradient performance. The system was designed from the ground up to marry the existing "SynGo" clinical console with an animal magnet. This application is led by the A.A. Martinos Center for Biomedical Imaging. We seek funding to (1) allow our many human users to use their imaging skills in animal models, and also (2) to allow the extensive technical work carried out for the human instruments to be made available to animal researchers, as well as expand the instrumentation available to researchers. We seek this instrumentation to allow the insights and developments carried out on animal systems to be rapidly translated to human use. At our center currently we have 237 trained and certified users of the human systems and 36 trained and certified users of the animal systems performing imaging on two animal and four human MRI systems, and more interaction between groups and investigators would greatly speed our funded research. We list 24 funded projects in support of this additional instrumentation.

描述（由申请人提供）：我们寻求7特斯拉平移MRI单元的资金：一个带有临床控制台的小动物系统（7 T/30 cm）。这种现成的设备将允许许多用户通过为两者提供相同的界面来在人类和动物成像之间进行转换。该系统由Siemens Medical Solutions和Bruker提供，与我们中心目前使用的计算机、射频系统和人机界面相匹配。所提出的系统将具有许多附加功能，使其成为最先进的仪器，包括32个RF接收器通道，多个高级脉冲序列，用于啮齿动物成像的定制RF线圈和强大的梯度性能。该系统的设计是从零开始，将现有的“SynGo”临床控制台与动物磁铁结合起来。这项申请是由A.A. Martinos生物医学成像中心。我们寻求资金（1）允许我们的许多人类用户在动物模型中使用他们的成像技能，以及（2）允许为动物研究人员提供人类仪器进行的广泛技术工作，以及扩大研究人员可用的仪器。我们寻求这种仪器，使动物系统的见解和发展能够迅速转化为人类使用。在我们的中心，目前我们有237名经过培训和认证的人类系统用户和36名经过培训和认证的动物系统用户在两个动物和四个人类MRI系统上进行成像，小组和研究人员之间的更多互动将大大加快我们资助的研究。我们列出了24个资助项目，以支持这一额外的仪器。

项目成果

A previously undescribed scene-selective site is the key to encoding ego-motion in naturalistic environments.

先前未描述的场景选择位点是在自然环境中编码自我运动的关键。

• DOI: 10.21203/rs.3.rs-3378081/v3
• 发表时间: 2024
• 期刊: Research square
• 作者: Kennedy,Bryan;Malladi,SaralaN;Tootell,RogerBH;Nasr,Shahin
• 通讯作者: Nasr,Shahin

Asymmetries in Global Perception Are Represented in Near- versus Far-Preferring Clusters in Human Visual Cortex.

人类视觉皮层中近处与远处偏好簇代表了全局感知的不对称性。

• DOI: 10.1523/jneurosci.2124-19.2019
• 发表时间: 2020
• 期刊: The Journal of neuroscience : the official journal of the Society for Neuroscience
• 作者: Nasr,Shahin;Tootell,RogerBH
• 通讯作者: Tootell,RogerBH

Scotopic Vision Is Selectively Processed in Thick-Type Columns in Human Extrastriate Cortex.

• DOI: 10.1093/cercor/bhaa284
• 发表时间: 2021-01-05
• 期刊: Cerebral cortex (New York, N.Y. : 1991)
• 作者: Tootell RBH;Nasr S
• 通讯作者: Nasr S