7T Translational MRI System

描述(由申请者提供)：我们为一个7特斯拉平移核磁共振装置寻求资金：一个带有临床控制台的小动物系统(7T/30厘米)。这种现成的设备将允许许多用户通过为人和动物提供相同的界面来在两者之间进行转换。该系统由西门子医疗解决方案公司和布鲁克公司提供，与我们中心目前使用的计算机、射频系统和用户界面相匹配。拟议的系统将具有许多其他功能，使其成为一种最先进的仪器，包括32个射频接收器通道、多个先进的脉冲序列、用于啮齿动物成像的定制射频线圈以及强大的梯度性能。该系统从头开始设计，将现有的“SynGo”临床控制台与动物磁铁结合在一起。该应用程序由A.A.Martinos生物医学成像中心领导。我们寻求资金是为了(1)允许我们的许多人类用户在动物模型中使用他们的成像技能，以及(2)允许为动物研究人员提供为人类仪器所进行的广泛技术工作，以及扩大研究人员可用的仪器。我们寻求这一工具，以使对动物系统进行的洞察和发展迅速转化为人类使用。在我们的中心，目前我们有237名经过培训和认证的人体系统用户，36名接受过培训和认证的动物系统用户，在两个动物和四个人类MRI系统上进行成像，团队和研究人员之间的更多互动将极大地加快我们资助的研究。我们列出了24个资助项目，以支持这一额外的工具。

DESCRIPTION (provided by applicant): We seek funding for a 7 Tesla translational MRI unit: a small animal system (7T / 30cm) with a clinical console. This off-the-shelf device will allow many users to translate between human and animal imaging by providing the same interface for both. The system is provided by Siemens Medical Solutions and Bruker, and matches the computers, RF system, and user interface of the human equipment currently in use at our center. The proposed system will have many additional features that make it a state-of-the-art instrument, including 32 RF receiver channels, multiple advanced pulse sequences, tailored RF coils for rodent imaging, and strong gradient performance. The system was designed from the ground up to marry the existing "SynGo" clinical console with an animal magnet. This application is led by the A.A. Martinos Center for Biomedical Imaging. We seek funding to (1) allow our many human users to use their imaging skills in animal models, and also (2) to allow the extensive technical work carried out for the human instruments to be made available to animal researchers, as well as expand the instrumentation available to researchers. We seek this instrumentation to allow the insights and developments carried out on animal systems to be rapidly translated to human use. At our center currently we have 237 trained and certified users of the human systems and 36 trained and certified users of the animal systems performing imaging on two animal and four human MRI systems, and more interaction between groups and investigators would greatly speed our funded research. We list 24 funded projects in support of this additional instrumentation.