ANATOMICALLY ACCURATE NEURAL NETWORKS: BUILDING A HIPPOCAMPUS

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。虚拟现实技术的发展，以及计算机图形学的惊人进步，现在允许实现极其复杂的算法来创建、显示和操纵详细神经元的现实网络。在这里，我们将一些工具应用到海马体的神经解剖模型中。将海马虚拟神经元组装成真实的神经网络，用于系统水平的电生理行为研究。由NINDS， NIMH和NSF联合资助的人类大脑项目资助R01 NS39600（这个持续的项目旨在以紧凑但足够完整和详细的方式描述树突结构，以便计算机生成形态学准确的神经元模型）。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The development of virtual reality techniques, and the breath-taking progress of computer graphics now allow for the implementation of extremely complex algorithms to create, display, and manipulate realistic networks of detailed neurons. Here, we apply some of the tools we have been developing to a neuroanatomical model of the hippocampus. Hippocampal virtual neurons will be assembled in realistic neural networks, and these will be used to study the electrophysiological behavior at the system level. Supported by Human Brain Project Grant R01 NS39600, funded jointly by NINDS, NIMH and NSF ( this continuing project is directed at describing dendritic structure in a compact yet sufficiently complete and detailed fashion to allow the computer generation of morphologically accurate neuronal models).