ANATOMICALLY ACCURATE NEURAL NETWORKS: BUILDING A HIPPOCAMPUS

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。虚拟现实技术的发展和计算机图形学的惊人进步现在允许实现极其复杂的算法来创建，显示和操纵逼真的详细神经元网络。在这里，我们应用一些工具，我们一直在开发的海马神经解剖模型。海马虚拟神经元将被组装在真实的神经网络中，这些神经网络将用于在系统水平上研究电生理行为。由NINDS，NIMH和NSF联合资助的人脑项目资助R 01 NS 39600（这个持续的项目旨在以紧凑但足够完整和详细的方式描述树突结构，以允许计算机生成形态学上准确的神经元模型）。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The development of virtual reality techniques, and the breath-taking progress of computer graphics now allow for the implementation of extremely complex algorithms to create, display, and manipulate realistic networks of detailed neurons. Here, we apply some of the tools we have been developing to a neuroanatomical model of the hippocampus. Hippocampal virtual neurons will be assembled in realistic neural networks, and these will be used to study the electrophysiological behavior at the system level. Supported by Human Brain Project Grant R01 NS39600, funded jointly by NINDS, NIMH and NSF ( this continuing project is directed at describing dendritic structure in a compact yet sufficiently complete and detailed fashion to allow the computer generation of morphologically accurate neuronal models).