HIV PREVALENCE, SEXUAL BEHAVIOR, AND ATTITUDES TOWARD CIRCUMCISION AMONG COLOMBIA

哥伦比亚的艾滋病毒感染率、性行为和对包皮环切术的态度

• 批准号: 7495232
• 负责人: Maria Cecilia Zea
• 金额: $ 46.51万
• 依托单位: GEORGE WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-04-01 至 2013-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7495232
• 关键词: AIDS prevention; AIDS/HIV problem; Accounting; Address; Adult; Affect; Africa; Age; American; Attention; Attitude; Beds; Behavior; Behavioral; Belief; Blood Tests; Capital; Caribbean natives; Caribbean region; Characteristics; Cities; Colombia; Communities; Computer Assisted; Condition; Conflict (Psychology); Country; Data; Demographic Factors; Depth; Development; Disruption; Enzyme-Linked Immunosorbent Assay; Epidemic; Female; Focus Groups; Future; Gays; Gray unit of radiation dose; HIV; Heterosexuals; High Prevalence; Homosexuality; Human immunodeficiency virus test; Immunoassay; Incidence; Individual; Internal Migrations; Intervention; Interview; Knowledge; Label; Latin America; Laws; Lead; Legal; Life; Link; Male Circumcision; Medical Surveillance; Methods; Modeling; Motivation; Multivariate Analysis; Numbers; Oral; Outcome; Participant; Pattern; Persons; Phase; Plague; Policies; Population; Poverty; Prevalence; Prevention; Prostitution; Public Health; Public Policy; Qualitative Research; Rate; Reaction; Recommendation; Recording of previous events; Research; Research Methodology; Respondent; Rights; Risk; Risk Behaviors; Sampling; Sex Behavior; Sexual Partners; Shapes; Social Class; Social Conditions; Social Environment; Social Network; Stigmata; Surveys; Techniques; Testing; Time; UNHCR; Urbanization; Violence; War; aged; base; demographics; design; displaced person; epidemiological model; experience; information gathering; innovation; life history; male; men; men who have sex with men; migration; oral HIV; programs; protective effect; psychologic; residence; response; social; social stigma; stem

DESCRIPTION (provided by applicant): This application describes a five-year research program that investigates individual, social, and structural influences on HIV risk and serostatus among men who have sex with men (MSM) in Bogota, Colombia. This study is of public health significance because it will contribute to knowledge concerning HIV prevalence and risk behavior in an understudied group at high risk for HIV. Moreover, it will evaluate the protection against HIV afforded by circumcision among MSM in Colombia. This application is innovative in its use of a conceptual framework that addresses HIV risk within the social and structural context. In Colombia, there are legal protections of the rights of all individuals, including gay men, while at the same time, there is ongoing civil unrest, forced displacement of large numbers of people, and homonegativity. This study investigates how such societal characteristics, as well as individuals' characteristics, influence vulnerability to HIV. The aims of the proposed study are 1) to examine structural, social, and individual factors relevant to HIV risk among MSM in Bogota; 2) to estimate prevalence of HIV among MSM in Bogota; 3) to explore the association between circumcision status and HIV serostatus and to investigate beliefs, knowledge, and attitudes concerning circumcision among Colombian MSM; and 4) to integrate information gained from the various research methods used and to draw conclusions that will guide the design of policies and interventions addressing HIV risk among MSM in Colombia. The research consists of three phases. Phase I involves qualitative research (12 key informant interviews, 10 focus groups, and 28 life history interviews) to explore the context of life for MSM in Bogota, including sexual behavior patterns, social networks, stigma associated with homosexuality and HIV, violence, migration, and displacement. Life history interviews will be conducted with MSM who have experienced displacement. Phase II involves quantitative research. Rapid oral HIV testing and a quantitative survey instrument will be administered with A-CASI to samples of MSM, aged 15 to 49. Social and structural data will reflect conditions in Bogota's19 localidades (localities) where participants live. Data will be used to test a model of HIV risk with both individual-level analyses and multi-level analyses (incorporating characteristics of the person and the locality of residence); to obtain estimates of HIV prevalence among MSM in the city; to examine protective effects of circumcision; and to describe attitudes and knowledge of circumcision. The pilot test includes 100 participants, and the full administration of the revised survey includes 1000 participants, all obtained through respondent-driven sampling. Phase III consists of triangulation of data and dissemination of findings. The contextualized information gained from this research will be useful in HIV prevention efforts for Colombian MSM at the societal, city, community, and individual levels. PUBLIC HEALTH RELEVANCE The proposed study will examine individual, social, and structural factors influencing HIV risk among Colombian MSM, and findings will be useful in designing targeted interventions. Elucidation of societal conditions that increase individuals' HIV vulnerability; identification of susceptible groups of people; and explication of the link between individual experiences, social/structural characteristics, and HIV risk will inform prevention efforts at multiple levels, including legal or policy changes and interventions aimed at the community or individuals.

描述(申请人提供)：本申请描述了一项为期五年的研究计划，该计划调查个人、社会和结构对哥伦比亚波哥大男男性行为者(MSM)艾滋病毒风险和血清状态的影响。这项研究具有公共卫生意义，因为它将有助于了解艾滋病毒流行率和艾滋病毒高危人群中未被研究的危险行为。此外，它还将评估哥伦比亚男男性同性恋者中包皮环切术对艾滋病毒的保护作用。这一应用程序在使用概念框架方面具有创新性，该框架在社会和结构范围内处理艾滋病毒风险。在哥伦比亚，包括男同性恋者在内的所有个人的权利都得到了法律保护，但与此同时，国内动乱仍在继续，大量人被迫流离失所，同性恋现象也在发生。这项研究调查了这些社会特征以及个人特征如何影响对艾滋病毒的易感性。这项拟议研究的目的是1)检查与波哥大男男性接触者中艾滋病毒风险相关的结构性、社会和个人因素；2)估计波哥大男男性接触者中艾滋病毒的流行率；3)探索包皮环切状况与艾滋病毒血清状态之间的关系，并调查哥伦比亚男男性接触者对包皮环切的信念、知识和态度；4)整合从使用的各种研究方法中获得的信息，并得出结论，以指导针对哥伦比亚男男性接触者中艾滋病毒风险的政策和干预措施的设计。研究分为三个阶段。第一阶段包括定性研究(12次关键线人访谈、10次焦点小组访谈和28次生活史访谈)，以探索波哥大男男性接触者的生活背景，包括性行为模式、社会网络、与同性恋和艾滋病毒有关的耻辱、暴力、移民和流离失所。将对经历过流离失所的男男性接触者进行生活史访谈。第二阶段涉及定量研究。将使用A-CASI对15至49岁的男男性接触者进行快速口腔艾滋病毒检测和定量调查仪器。社会和结构数据将反映参与者居住的波哥大19个地区(地区)的情况。数据将用于测试艾滋病毒风险模型，包括个人水平分析和多水平分析(结合个人和居住地的特征)；获得该市男男性接触者中艾滋病毒流行率的估计；检查包皮环切术的保护效果；以及描述包皮环切术的态度和知识。试点测试包括100名参与者，修订后的调查的全面管理包括1000名参与者，所有参与者都是通过受访者驱动的抽样获得的。第三阶段包括数据的三角测量和结果的传播。从这项研究中获得的背景信息将有助于哥伦比亚MSM在社会、城市、社区和个人层面上预防艾滋病毒的努力。 公共卫生相关性拟议的研究将审查影响哥伦比亚男男性接触者艾滋病毒风险的个人、社会和结构性因素，研究结果将有助于设计有针对性的干预措施。阐明增加个人艾滋病毒易感性的社会条件；确定易感人群；阐明个人经历、社会/结构特征与艾滋病毒风险之间的联系，将为多个层面的预防工作提供信息，包括法律或政策变化以及针对社区或个人的干预措施。