Training in Molecular Virology and Pathogenesis

申请者描述(由申请人提供)：本申请是为4名博士生继续分子病毒学和发病机制方面的培训计划。来自康奈尔大学整个校园的9名病毒学家参加了此次培训，其中包括兽医学院微生物学和免疫学系，以及分子生物学、遗传学和植物病理学系，此外还有博伊斯·汤普森研究所的一名病毒学家。该计划的共同主题是分子病毒学以及病毒与宿主细胞和组织之间的相互作用。这些实验室涉及各种不同的病毒系统，包括疱疹病毒复制和发病机制、流感和冠状病毒细胞感染、细小病毒宿主范围、呼肠孤病毒和杯状病毒细胞复制机制、逆转录病毒衣壳组装、杆状病毒复制以及植物病毒与其宿主细胞运输途径之间的相互作用。这些领域为学生提供了许多机会来研究控制病毒复制和随后的宿主感染的基本分子机制。对病毒学感兴趣的学生是通过康奈尔大学各地的几个研究生领域(校园范围的研究生项目)招募的，这些领域吸引了大量具有不同背景的合格申请者。参加该项目的学生在第一年在不同的实验室完成3次轮换，然后选择一个实验室进行研究生培训。一旦学生选择了病毒学的实验室和项目，这个项目就会为他们的项目的2-4年级的学生提供支持。对学生培训的监督涉及学生的导师、由全校成员组成的特别委员会以及培训计划的执行委员会。学生可以参加一系列协调一致的课程，包括病毒学的两门核心课程，以及其他许多相关学科的课程，其中包括免疫学、生物化学和分子生物学的各种主题。与该计划相关的活动包括来自整个大学的教师参与的活动，包括每周一次的病毒学期刊俱乐部，病毒学及相关主题的研讨会，以及病毒学、感染生物学和发病机制方面的务虚会。

DESCRIPTION (provided by applicant): This application is to continue a training program in molecular virology and pathogenesis for 4 PhD students. This training program involves 9 virologists from Cornell University throughout the campus, including the Department of Microbiology and Immunology in the College of Veterinary Medicine, as well as the Departments of Molecular Biology and Genetics, and Plant Pathology, in addition to one virologist at the Boyce Thompson Institute. The common themes of the program are in molecular virology and the interactions between viruses and their host cells and tissues. The laboratories involved work on a variety of different viral systems, including herpesvirus replication and pathogenesis, influenza and coronavirus cell infection, parvovirus host range, reovirus and calicivirus cell replication mechanisms, retrovirus capsid assembly, baculovirus replication, and the interactions between plant viruses and their host cell transport pathways. These areas offer students many opportunities to examine the fundamental molecular mechanisms that control viral replication and the subsequent infection of the host. Students interested in virology are recruited through several graduate fields (campus-wide graduate programs) from throughout Cornell, which draw on large pools of well-qualified applicants with varying backgrounds. Students entering the program complete 3 rotations in different laboratories in their first year then choose a laboratory for their graduate training. This program supports students between Years 2 and 4 of their projects once they have chosen a laboratory and project in virology. Oversight of the student's training involves the student's mentor, the special committee with members from throughout the university, and the executive committee of the training program. A coordinated series of courses are available to the students, including two core courses in virology, and many others in relevant subjects which include various topics in immunology, biochemistry and molecular biology. Associated with the program are activities that involve faculty from throughout the university, including a weekly virology journal club, seminars in virology and related topics, and retreats in virology and infection biology and pathogenesis.