Biomedical Simulations Resource

南加州大学的生物医学模拟资源（BMSR）于9月成立 1985年通过NIH国家研究资源中心批准号RR-01861。BMSR是 致力于通过技术进步的最先进的生物医学建模和仿真 研究与开发（核心）和合作研究项目。它还寻求传播这一 通过服务、培训和传播活动， 整个社区。后者的活动包括开发和分发建模/模拟软件，简称 课程、讲习班和出版研究卷-除了公开文献出版物之外。的重点 核心研究项目是开发先进的建模和仿真方法， 应用于生理系统，以促进知识和改善临床实践。的 非线性动态系统，稀疏数据建模，闭环生理控制和多变量的挑战性案例 复杂的系统，构成这一努力的重点。核心项目制定的方法 是这一领域研究的前沿他们的有效研究是可能的计算设施， 人力资源集中在BMSR中。这些方法的实际应用涵盖了各种 生理领域，包括药代动力学、心肺、代谢、神经和感觉系统。 作为所开发方法的试验场和传播手段的其他应用包括： 在我们的合作项目中。以用户友好的方式实施充分开发和测试的方法 软件包，并提供给整个生物医学界。 BMSR的服务、培训和传播活动旨在促进知识交流， 生物医学建模与仿真技术。他们还旨在创建一个互动的社区， 研究人员，可提供跨越障碍所需的多学科科学/技术动力 这是由主题的复杂性决定的。BMSR的最终目标是促进模拟的转移 科技应用于临床环境，以改善我们的医疗体系。

The Biomedical Simulations Resources (BMSR) at the University of Southern California was established in September 1985 through Grant No. RR-01861 from the National Center for Research Resources of the NIH. The BMSR is dedicated to the advancement of the state-of-the-art in biomedical modeling and simulation through Technological Research and Development (Core) and Collaborative Research projects. It also seeks the dissemination of this knowledge and related software through Service, Training and Dissemination activities aimed at the biomedical community at large. The latter activities include development and distribution of modeling/simulation software, short courses, workshops and publication of research volumes - in addition to publications in open literature. The emphasis of the Core Research projects is on development of advanced modeling and simulation methodologies and their application to physiological systems for the advancement of knowledge and improvement of clinical practice. The challenging cases of nonlinear dynamic systems, sparse data modeling, closed-loop physiological control, and multivariate complex systems, constitute the focal points of this effort. The methodologies developed by the Core projects are at the cutting-edge of research in this area. Their effective study is made possible by the computing facilities and human resources that are brought together in the BMSR. Pivotal applications of these methodologies cover a variety of physiological domains, including pharmacokinetics, cardio-respiratory, metabolic, neural and sensory systems. Additional applications, serving as testing grounds and disseminations means for the developed methodologies, are made in our Collaborative projects. Fully developed and tested methodologies are implemented in user-friendly software packages and made available to the biomedical community at large. The Service, Training and Dissemination activities of the BMSR seek to promote the exchange of knowledge and technology in the area of biomedical modeling and simulation. They also aim at creating an interactive community of investigators, which can provide the multi-disciplinary scientific/technological impetus needed to transcend the barriers imposed by the complexity of the subject. The ultimate objective of the BMSR is to facilitate transfer of simulation science and technology to the clinical environment for the improvement of our health care system.