2008 FASEB Summer Research Conference on Biological Methylation: from DNA to Hist

描述（由申请人提供） 该提案要求为2008年夏季FASEB（美国实验生物学学会联合会）会议“生物甲基化：从DNA到组蛋白”提供部分资金（约25%）。会议将重点关注表观遗传甲基化及其对人类疾病影响的前沿研究，这是NIEHS当前的主要任务之一。 会议将于2008年6月1日至6日（星期日至星期五）在亚利桑那州无忧无虑的无忧无虑度假村举行。FASEB生物甲基化会议是该领域最具刺激性和重要性的会议之一，约有150名科学家（包括许多知名女科学家，年轻科学家，研究生和博士后研究员）聚集在一起，协调，交流和传播信息，并探索人类疾病的表观遗传因素（如环境因素，个体易感性和年龄）。 1名主旨发言人、9名会议主席、36名特邀发言人和18名发言人（青年科学家）将从提交的摘要中选出以下9个主题：1）真核细胞胞嘧啶甲基转移酶; 2）DNA甲基化与组蛋白甲基化的联系; 3）组蛋白赖氨酸甲基化和识别; 4）蛋白质精氨酸甲基化; 5）DNA甲基化与疾病; 6）表观遗传学与癌症; 7）组蛋白去甲基化; 8）除组蛋白或核酸以外的甲基化;和，9）小分子酶抑制剂。 此外，三个下午的小型研讨会是专门为年轻的研究人员。

DESCRIPTION (provided by applicant) This proposal requests partial funding (~25%) for 2008 Summer FASEB (Federation of American Societies for Experimental Biology) conference on "Biological Methylation: from DNA to Histones". The meeting will focus on the forefront research of epigenetic methylation and its influences on human illnesses, which is one of the current major missions of the NIEHS. The conference will be held in the Carefree Resort, Carefree, Arizona, from June 1-6, 2008 (Sunday-Friday). The FASEB Biological Methylation Conference is one of the most stimulating and important meetings in the field, where approximately 150 scientists (including many established women scientists, younger scientists, graduate students, and postdoctoral fellows) assemble to coordinate, exchange, and disseminate information and to explore epigenetic factors (such as environmental factors, individual susceptibility and age) on human illnesses. One keynote speaker, 9 session chairs, 36 invited speakers and 18 speakers (young scientists) selected from submitted abstracts will address the following 9 major themes: 1) eukaryotic cytosine methyltransferases; 2) link DNA methylation to histone methylation; 3) histone lysine methylation and recognition; 4) protein arginine methylation; 5) DNA methylation and diseases; 6) epigenetics and cancers; 7) histone demethylation; 8) methylation other than histones or nucleic acids; and, 9) small molecule enzyme inhibitors. In addition, three afternoon mini-symposia are devoted to young investigators.