2008 FASEB Summer Research Conference on Biological Methylation: from DNA to Hist

2008 FASEB 夏季生物甲基化研究会议：从 DNA 到 Hist

• 批准号: 7483969
• 负责人: Xiaodong Cheng
• 金额: $ 0.8万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-05-01 至 2009-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7483969
• 关键词: Address; Age; American; Arginine; Arizona; Biochemistry; Biological; Biology; Collaborations; Cytosine; DNA Methylation; Disease; Environmental Risk Factor; Enzyme Inhibitor Drugs; Enzyme Inhibitors; Epigenetic Process; Funding; Goals; Histones; Human; Individual; Link; Lysine; Malignant Neoplasms; Methionine; Methylation; Methyltransferase; Mission; Modification; Nucleic Acids; Participant; Postdoctoral Fellow; Predisposition; Proteins; Reaction; Request for Proposals; Research; Research Personnel; Resort; S-Adenosylmethionine; Scientist; Societies; Students; Woman; abstracting; demethylation; interest; methylcobalamin-coenzyme M methyltransferase; programs; research and development; small molecule; symposium

DESCRIPTION (provided by applicant) This proposal requests partial funding (~25%) for 2008 Summer FASEB (Federation of American Societies for Experimental Biology) conference on "Biological Methylation: from DNA to Histones". The meeting will focus on the forefront research of epigenetic methylation and its influences on human illnesses, which is one of the current major missions of the NIEHS. The conference will be held in the Carefree Resort, Carefree, Arizona, from June 1-6, 2008 (Sunday-Friday). The FASEB Biological Methylation Conference is one of the most stimulating and important meetings in the field, where approximately 150 scientists (including many established women scientists, younger scientists, graduate students, and postdoctoral fellows) assemble to coordinate, exchange, and disseminate information and to explore epigenetic factors (such as environmental factors, individual susceptibility and age) on human illnesses. One keynote speaker, 9 session chairs, 36 invited speakers and 18 speakers (young scientists) selected from submitted abstracts will address the following 9 major themes: 1) eukaryotic cytosine methyltransferases; 2) link DNA methylation to histone methylation; 3) histone lysine methylation and recognition; 4) protein arginine methylation; 5) DNA methylation and diseases; 6) epigenetics and cancers; 7) histone demethylation; 8) methylation other than histones or nucleic acids; and, 9) small molecule enzyme inhibitors. In addition, three afternoon mini-symposia are devoted to young investigators.

描述（由申请人提供） 该提案要求为 2008 年夏季 FASEB（美国实验生物学会联合会）“生物甲基化：从 DNA 到组蛋白”会议提供部分资金（约 25%）。会议将重点关注表观遗传甲基化及其对人类疾病影响的前沿研究，这是NIEHS当前的主要任务之一。 会议将于2008年6月1日至6日（周日至周五）在亚利桑那州Carefree度假村举行。 FASEB生物甲基化会议是该领域最激动人心和最重要的会议之一，约有150名科学家（包括许多知名女科学家、年轻科学家、研究生和博士后）齐聚一堂，协调、交流和传播信息，并探索人类疾病的表观遗传因素（如环境因素、个人易感性和年龄）。 一名主讲人、9 名分会主席、36 名特邀演讲者和从提交的摘要中选出的 18 名演讲者（青年科学家）将讨论以下 9 个主题：1）真核胞嘧啶甲基转移酶； 2）将DNA甲基化与组蛋白甲基化联系起来； 3）组蛋白赖氨酸甲基化和识别； 4) 蛋白质精氨酸甲基化； 5）DNA甲基化与疾病； 6）表观遗传学和癌症； 7) 组蛋白去甲基化； 8)组蛋白或核酸以外的甲基化； 9) 小分子酶抑制剂。 此外，三个下午的小型研讨会专门针对年轻研究人员。