Principles of STD and HIV Research

描述（由申请人提供）：性病和艾滋病毒研究的原则年度课程首次于1993年举行，提供了在性病/艾滋病毒领域从事研究所需的技能的密集概述。自那时以来，已有600多名学员参加，其中许多是妇女或少数种族/族裔。跨学科性传播疾病/艾滋病毒研究的重要性已成为设计研究和获得资金的关键。熟悉自己学科之外的研究视角为年轻的研究人员提供了持续跨学科学习和合作的工具，并保持了广泛的调查可能性。本课程提供了一个独特的机会，在行为，临床，流行病学，统计和发病机制研究的介绍性培训，通过提供这些广泛的学科共同的语言和技能的实际导向的概述。课程时间限制在两周内，以鼓励正在建立积极的研究事业的个人，并允许那些居住在当地以外的人参加。课程目标是：（1）向年轻的研究人员介绍性传播疾病/艾滋病毒领域的关键研究领域和问题;（2）向研究人员介绍进行科学和道德研究所需的研究技术和工具，包括研究设计、实验方法、数据收集工具的开发、人类受试者的考虑和数据分析; 3）向学员介绍性病/艾滋病研究所涉及的不同学科的基本知识，以促进研究合作;以及4）讨论成功竞争研究基金和发表自己工作的战略。该课程整合了六个轨道：1）性病/艾滋病跨学科研究的要点; 2）感染的临床和流行病学方面; 3）特定感染的发病机制; 4）行为研究的方法; 5）成功和道德研究的策略;和6）生物统计分析的关键主题。课程记录以两卷参考资料活页夹分发，其中载有演讲者的幻灯片和主要参考资料。在过去的几年里，该课程主要从NIH性病合作研究中心（CRC）获得财政和教师支持。自1998年以来，CRC每年都为教师或学生提供旅行支持。由于目前被指定为性传播感染和局部杀微生物剂合作研究中心的性传播疾病防治中心目前正在进行竞争性更新，因此2004年课程的资金将无法通过该机制获得。因此，本提案寻求通过R13机制获得同等资金。

DESCRIPTION (provided by applicant): The Annual Course on Principles of STD and HIV Research was first held in 1993 to provide an intensive overview of skills needed to pursue a research career in the field of STD/HIV. Since then, over 600 trainees, many of whom were women or racial/ethnic minorities, have attended. The importance of cross-disciplinary STD/HIV research has become essential in designing studies and in obtaining funding. Establishing familiarity with research perspectives outside one's own discipline provides young investigators with tools for continued interdisciplinary learning and collaboration, and for maintaining a broad scope of investigative possibilities. This course offers a unique opportunity for introductory training in behavioral, clinical, epidemiologic, statistical and pathogenesis research by providing a practically oriented overview of language and skills common to these broad disciplines. Course duration is limited to two weeks to encourage individuals who are establishing active research careers and allow those who reside outside of the local area to attend. Course objectives are to: 1) Introduce young investigators to critical research areas and questions in the field of STD/HIV; 2) Expose investigators to research techniques and tools needed to conduct scientifically and ethically sound studies, including study design, experimental approach, development of instruments for data collection, human subjects considerations, and data analysis; 3) Introduce trainees to fundamentals of different disciplines involved in STD/HIV research in order to foster research collaborations; and 4) Discuss strategies for successfully competing for research funds and publishing one's work. The course integrates six tracks: 1) Essentials of STD/HIV interdisciplinary research; 2) Clinical and epidemiologic aspects of infections; 3) Pathogenesis of specific infections; 4) Methodology of behavioral research; 5) Strategies for successful and ethical research; and 6) Critical topics in biostatistical analysis. The course proceedings are disseminated in a two-volume reference binder containing speakers' slides and key references. In past years, the course derived financial and faculty support primarily from the NIH STD Cooperative Research Centers (CRC). Since 1998, the CRCs have each annually contributed in the form of travel support for faculty or students. Because the STD CRCs, now designated the Sexually Transmitted Infections and Topical Microbicides Cooperative Research Centers (STI TM CRCs), are currently up for competitive renewal, funding for the 2004 course will not be available through that mechanism. For this reason, the current proposal seeks to obtain equivalent funding through the R13 mechanism.