Principles of STD and HIV Research

简介（由申请人提供）：性传播疾病和艾滋病毒研究原理年度课程于1993年首次举办，旨在提供在性传播疾病和艾滋病毒领域从事研究工作所需技能的深入概述。从那时起，有600多名学员参加了培训，其中许多是妇女或少数民族。在设计研究和获得资助方面，跨学科性传播疾病/艾滋病毒研究的重要性已经变得至关重要。熟悉自己学科以外的研究视角，为年轻的研究者提供了继续进行跨学科学习和合作的工具，并保持了广泛的研究可能性。本课程为行为学、临床学、流行病学、统计学和发病机制研究提供了一个独特的入门培训机会，提供了这些广泛学科共同的语言和技能的实践导向概述。课程持续时间限制为两周，以鼓励那些正在建立积极的研究事业的个人，并允许那些居住在当地以外的人参加。课程目标是：1)向年轻研究者介绍性病/艾滋病领域的关键研究领域和问题；2)让调查人员了解开展科学和合乎伦理的研究所需的研究技术和工具，包括研究设计、实验方法、数据收集工具的开发、人类受试者考虑和数据分析；3)向学员介绍性病/艾滋病研究中不同学科的基础知识，以促进研究合作；4)讨论成功竞争研究基金和发表研究成果的策略。本课程包括六个方向：1)性病/艾滋病跨学科研究要点；2)感染的临床和流行病学方面；3)特异性感染的发病机制；4)行为研究方法论；5)成功和合乎伦理的研究策略；6)生物统计分析中的关键主题。课程论文集以两卷本的参考资料夹分发，其中载有演讲者的幻灯片和主要参考资料。在过去的几年中，该课程主要从美国国立卫生研究院性病合作研究中心（CRC）获得财政和教师支持。自1998年以来，中心每年都以支持教师或学生旅行的形式作出贡献。由于性病研究中心（现在被指定为性传播感染和局部杀微生物剂合作研究中心）目前正在进行竞争性更新，2004年课程的经费将无法通过该机制获得。出于这个原因，目前的提案寻求通过R13机制获得同等的资金。

DESCRIPTION (provided by applicant): The Annual Course on Principles of STD and HIV Research was first held in 1993 to provide an intensive overview of skills needed to pursue a research career in the field of STD/HIV. Since then, over 600 trainees, many of whom were women or racial/ethnic minorities, have attended. The importance of cross-disciplinary STD/HIV research has become essential in designing studies and in obtaining funding. Establishing familiarity with research perspectives outside one's own discipline provides young investigators with tools for continued interdisciplinary learning and collaboration, and for maintaining a broad scope of investigative possibilities. This course offers a unique opportunity for introductory training in behavioral, clinical, epidemiologic, statistical and pathogenesis research by providing a practically oriented overview of language and skills common to these broad disciplines. Course duration is limited to two weeks to encourage individuals who are establishing active research careers and allow those who reside outside of the local area to attend. Course objectives are to: 1) Introduce young investigators to critical research areas and questions in the field of STD/HIV; 2) Expose investigators to research techniques and tools needed to conduct scientifically and ethically sound studies, including study design, experimental approach, development of instruments for data collection, human subjects considerations, and data analysis; 3) Introduce trainees to fundamentals of different disciplines involved in STD/HIV research in order to foster research collaborations; and 4) Discuss strategies for successfully competing for research funds and publishing one's work. The course integrates six tracks: 1) Essentials of STD/HIV interdisciplinary research; 2) Clinical and epidemiologic aspects of infections; 3) Pathogenesis of specific infections; 4) Methodology of behavioral research; 5) Strategies for successful and ethical research; and 6) Critical topics in biostatistical analysis. The course proceedings are disseminated in a two-volume reference binder containing speakers' slides and key references. In past years, the course derived financial and faculty support primarily from the NIH STD Cooperative Research Centers (CRC). Since 1998, the CRCs have each annually contributed in the form of travel support for faculty or students. Because the STD CRCs, now designated the Sexually Transmitted Infections and Topical Microbicides Cooperative Research Centers (STI TM CRCs), are currently up for competitive renewal, funding for the 2004 course will not be available through that mechanism. For this reason, the current proposal seeks to obtain equivalent funding through the R13 mechanism.