课题基金 / 基金详情

Identifying the Causal Alleles for SLE in the SLAM Locus on Human chromosome 1q23

Identifying the Causal Alleles for SLE in the SLAM Locus on Human chromosome 1q23
识别人类染色体 1q23 SLAM 基因座中 SLE 的致病等位基因
批准号：
7491057
负责人：
Timothy James Vyse
金额：
$13.63万
依托单位：
BETH ISRAEL DEACONESS MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/7491057
关键词：
1q23AddressAffectAllelesAnimalsAntibody FormationAntigen-Antibody ComplexAntigen-Presenting CellsApoptoticAutoantibodiesAutoantigensB-LymphocytesBackcrossingsBacteriaBreedingC57BL/6 MouseCD4 Positive T LymphocytesCell NucleusCell physiologyCellsChromatinChromosomes, Human, Pair 1CodeCommitDefectDendritic CellsDevelopmentDiseaseDisruptionElementsEmbryoExcisionExonsFamilyGene FamilyGene TargetingGene Transfer TechniquesGenesGenetic Predisposition to DiseaseGenomeGenomic SegmentGenomicsGlomerulonephritisHaplotypesHelper-Inducer T-LymphocyteHematopoiesisHematopoieticHematopoietic stem cellsHumanHuman ChromosomesIn VitroKnock-in MouseKnock-outKnockout MiceLeadLupusLupus ErythematosusLymphocyte antigenLymphoidMediatingMinorMononuclearMouse StrainsMusMutationNumbersPan GenusPathogenesisPathway interactionsPatientsPhagocytesPhenotypePhysiologicalPlayPredispositionPrincipal InvestigatorProductionProtein IsoformsRefuse DisposalResearch PersonnelRoleSerumSeverity of illnessStem cellsSurfaceSusceptibility GeneSyndromeSystemSystemic Lupus ErythematosusT-Cell DevelopmentT-LymphocyteTechnologyTestingTherapeuticThinkingTissuesTransgenesTransgenic OrganismsVariantbasechronic autoimmune diseasecongenicembryonic stem cellexperiencegene functiongenetic analysishomologous recombinationin vivomacrophageneutrophilreceptorresearch studyresponseskills

项目摘要

项目成果

Timothy James Vyse的其他基金

相似基金

相关文献

中文摘要
翻译
未提供摘要
英文摘要
ABSTRACT NOT PROVIDED
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Identifying the Causal Alleles for SLE in the SLAM Locus on Human chromosome 1q23
SLE and UC Study
Systemic Lupus Erythematosus and Ulcerative Colitis Study
SLE and UC Study
海外基金