PS06-011, HIV Prevention Research with HIV+ Incarcerated Populations

PS06-011，艾滋病毒监禁人群的艾滋病毒预防研究

• 批准号: 7284292
• 负责人: FREDERICK LEWIS ALTICE
• 金额: $ 40万
• 依托单位: AIDS PROJECT HARTFORD, INC.
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-01 至 2009-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7284292
• 关键词: PS06; 011; HIV; Prevention; Research

DESCRIPTION (provided by applicant): ABSTRACT: The prevalence of HIV among prisoners is several-fold greater than found in the general community. Over one quarter of all HIV+ individuals cycle through the U.S. correctional system annually. Correctional facilities are a structured, but important point of contact for high risk HIV+ individuals who return to our communities. To date, there have not been fully comprehensive prison-release programs that are designed to meet the needs of released prisoners and their community. They have primarily been predicated only on various case management models and have not demonstrated continued stability in HIV outcomes after release. Hence, integrated programs have lacked adherence to antiretroviral therapy and reduction in HIV risk taking interventions for HIV+ prisoners transitioning to the community. In this proposal, we seek to integrate two existing programs in Connecticut (Project TLC and Project CONNECT) and layer on a modified HIV risk reduction intervention, adapted from the Holistic Health Recovery Program (HHRP), to be administered within prison and as a booster session three months after release. We intend to modify the HHRP to a four-session intervention within the prison setting during the 90 days prior to release. We will call this the Pre-Release Healthy Transition (PHT). Combining the PHT with the existing Project TLC (transitional case management services for released prisoners) and Project CONNECT (a randomized controlled trial of directly administered antiretroviral therapy versus standard of care for opioid dependent patients who are linked to opiate agonist therapy after release) will result in the comprehensive prison release program now called Project TLC+. The availability of existing resources for Project TLC and Project CONNECT allow for the infrastructure to fully implement a comprehensive transitional program for HIV+ prisoners. Additional strengths of this proposal are the collaborations between a community based organization experienced with prison release programs (AIDS Project Hartford), the HIV in Prisons Program at Yale University, and the Connecticut Departments of Correction and Public Health. The existing resources, the strong collaborations, the experience of the investigators working in community and correctional settings and past track record of these programs markedly influence the likelihood of successfully implementing an effective intervention and completing the proposed research.

描述（由申请人提供）：摘要：艾滋病毒在囚犯中的流行率是一般社区的几倍。每年，超过四分之一的艾滋病毒阳性者在美国的惩教系统中循环。惩教设施是一个结构化的，但重要的接触点的高风险艾滋病毒+个人谁返回我们的社区。迄今为止，还没有一个旨在满足获释囚犯及其社区需要的全面的监狱释放方案。它们主要是根据各种病例管理模式预测的，并没有显示出释放后艾滋病毒结果的持续稳定性。因此，综合方案缺乏对抗逆转录病毒治疗的坚持，也没有减少对向社区过渡的艾滋病毒阳性囚犯采取艾滋病毒风险干预措施。在这项提案中，我们寻求整合康涅狄格州现有的两个项目（TLC项目和BECT项目），并在修改后的艾滋病毒风险降低干预措施上分层，该干预措施改编自整体健康恢复计划（HRP），将在监狱内管理，并在释放后三个月作为助推器会议。我们打算将HRP修改为在释放前90天内在监狱环境中进行四次干预。我们称之为发布前健康过渡（PHT）。将PHT与现有的TLC项目（释放囚犯的过渡性病例管理服务）和PECT项目（一项针对释放后与阿片激动剂治疗有关的阿片类药物依赖患者的直接抗逆转录病毒治疗与标准治疗的随机对照试验）相结合，将导致全面的监狱释放计划，现在称为TLC+项目。TLC项目和BACECT项目现有资源的可用性使基础设施能够充分实施针对艾滋病毒阳性囚犯的全面过渡方案。这项建议的其他优势是一个社区组织之间的合作经验丰富的监狱释放方案（艾滋病项目哈特福德），艾滋病毒在监狱计划在耶鲁大学，和康涅狄格州的矫正和公共卫生部门。现有的资源，强有力的合作，在社区和矫正环境中工作的调查人员的经验和这些计划的过去的跟踪记录显着影响成功实施有效的干预和完成拟议的研究的可能性。