PS06-011, HIV Prevention with HIV+ Incarcertated Men

描述（由申请人提供）：本可行性研究将测试主要针对非裔美国人、拉丁美洲人和白色HIV阳性囚犯（200名男性，每种条件随机分配100名）、年龄18岁及以上的同伴领导小组水平干预的有效性。该干预措施旨在通过促进禁欲、一夫一妻制和使用避孕套以及增加获得适当医疗的机会和出狱后的预防服务来减少艾滋病毒传播。干预措施将与PA惩教部的护理标准进行比较。这项拟议的研究有6个目标，即：（1）测试旨在减少艾滋病毒风险行为的干预措施的有效性，与即将发布的艾滋病毒阳性男性的标准护理相比（2）测试干预措施的有效性，以增加从监狱释放后获得适当的药物滥用治疗和预防复发服务的机会;（3）测试干预措施是否有助于提高对伴侣咨询转介服务的态度和技能;（4）测试干预措施是否有助于增加获得护理的机会，包括社会服务和医疗;（5）测试干预措施是否有助于提高处于干预条件下的男子利用服务促进坚持医疗的能力;（6）将干预的成本和收益与标准护理进行比较。参与者将获得非货币激励，以尽量减少流失，并在干预前、干预后2周、3个月和6个月完成评估。这些措施包括：（1）艾滋病毒传播风险;（2）与性伴侣沟通;（3）获得和利用药物滥用治疗;（4）获得和利用与艾滋病有关的保健和社会服务。将采用多元回归和逻辑回归对目标进行统计学评价。

DESCRIPTION (provided by applicant): This feasibility study will test the efficacy of a peer led group level intervention primarily targeting African American, Latino American, and White HIV+ inmates (200 men, 100 randomized per condition), age 18 and older. The intervention is designed to reduce HIV transmission by promoting abstinence, monogamy, and using condoms as well as increase access to appropriate medical treatment, and prevention services after release from prison. The intervention will be compared against the PA Dept of Corrections standard of care. The proposed study is guided by 6 aims, to: (1) Test the efficacy of an intervention designed to reduce HIV risk behavior compared to the standard of care among HIV+ men soon to be released (within 6 months) from a state prison; (2) Test the efficacy of the intervention to increase access to appropriate substance abuse treatment and relapse prevention services after release from prison; (3) Test the intervention to increase attitudes and skills related to partner counseling referral services (PCRS); (4) Test the efficacy of the intervention to increase access to care, including social services and medical treatment; (5) Test the efficacy of the intervention to increase the abilities of men in the intervention condition to utilize services to promote adherence to medical treatment; and (6) Compare the intervention's costs and benefits to the standard of care. Participants will receive non-monetary incentives to minimize attrition, and complete assessments before the intervention, at 2 weeks, 3, and 6 months post. Measures include (1) HIV transmission risks; (2) communicating with sexual partners; (3) access and utilization of substance abuse treatment, and, (4) access and utilization of AIDS-related health and social services. The aims will be evaluated statistically with multiple regression and logistic regression.