Georgian Implementation Science Fogarty Training Program (GIFT)

格鲁吉亚实施科学福格蒂培训计划 (GIFT)

• 批准号: 10688700
• 负责人: FREDERICK LEWIS ALTICE
• 金额: $ 29.13万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-04-01 至 2028-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10688700
• 关键词: AIDS prevention; Biometry; Biostatistical Methods; Central Asia; Collaborations; Communities; Counseling; Data; Databases; Discrimination; Eastern Europe; Educational Curriculum; Elements; Epidemic; Evidence based intervention; Faculty; Government; HIV; Hybrids; Infection; Injecting drug user; Institution; Institutionalization; Knowledge; Learning; Medicine; Mentors; Modeling; Needle-Exchange Programs; Outcome; Phase; Population; Populations at Risk; Prevalence; Public Health; Research; Research Methodology; Research Personnel; Resources; Student recruitment; Teacher Professional Development; Testing; Time; Training; Training Programs; Universities; design; doctoral student; experience; implementation research; implementation science; implementation trial; international partnership; low and middle-income countries; men who have sex with men; mortality; next generation; opioid agonist therapy; pre-exposure prophylaxis; prevent; programs; skills; social stigma; treatment as prevention

Despite many available evidence-based interventions (EBIs) to prevent HIV, new infections and mortality in Georgia have increased by 30% and 335%, respectively. Georgia is a LMIC with HIV prevalence of 0.4% and concentrated in key at-risk populations (KAPs) like MSM and PWID, where the epidemic is growing fastest. Though all the elements of the HIV prevention toolkit are present in Georgia (voluntary counseling/testing [VCT], pre-exposure prophylaxis [PrEP], opioid agonist therapies [OAT], syringe services programs [SSPs] and treatment as prevention [TasP]), they are markedly under-scaled in terms of coverage and, importantly, are not adequately implemented in KAPs. In addition to suboptimal implementation of HIV prevention, Georgia’s ability to control its epidemic has been hampered by its lack of expertise in biostatistics. This expertise is need not only to analyze a rich array of databases that could guide more effective implementation in real-time, but in its ability to rigorously design, implement and analyze data from implementation trials, which are urgently needed in the Georgian context where the epidemic is concentrated in KAPs and where stigma and discrimination abounds. To meet this need, we propose to develop and institutionalize the Georgian Implementation Science Fogarty Training (GIFT) program at Ilia State University (ISU), the leading research institution in Georgia, in collaboration with Yale University. GIFT will leverage the combined resources of Yale University (Medicine and Public Health) with ISU, through provision of long-, mid-, and short-term training. GIFT will focus on HIV prevention through advanced training in biostatistics and implementation research methods. Specifically, GIFT adheres to three core aims, including to: 1) train 4 GIFT faculty in Year 1, followed by 6 doctoral students recruited in Years 2 and 3, who will focus their training on HIV prevention and who will receive advanced training in biostatistics and implementation research methods through a hybrid learning program; 2) transfer knowledge and build capacity within ISU, the Caucasus and Eastern Europe and Central Asia through short-term training at a Summer Bootcamp; and 3) develop the HIV Implementation Science and Biostatistical Methods Resource Hub to consolidate resources and build partnerships for better population outcomes. All doctoral students will be paired with ISU and Yale mentors and gain real-world experience analyzing data from HIV implementation trials now underway or completed at Yale. Training resources will be contextualized for the HIV epidemic in Georgia. Building on prior experience with Fogarty training programs and existing successful collaborations and partnerships between Yale and ISU, we are poised to train the next generation of public health researchers more effectively, recognizing the need for better implementation with HIV prevention in KAPs. GIFT will provide advanced training to produce a phased transfer of knowledge, skills and expertise from Yale to ISU over the course of five years, resulting in a model curriculum for training at Georgia’s top research university, with strong support by regional and local faculty and commitment by community, government and international partnerships.

尽管有许多可用的循证干预措施(EBI)来预防艾滋病毒、新的感染和死亡 佐治亚州分别增加了30%和335%。格鲁吉亚是一个低收入国家，艾滋病毒流行率为0.4%， 集中在MSM和PWID等疫情增长最快的关键高危人群(KAP)。 虽然艾滋病毒预防工具包的所有要素都在格鲁吉亚(自愿咨询/检测[自愿咨询/检测]， 暴露前预防[PrEP]、阿片类激动剂治疗[OAT]、注射器服务计划[SSP]和 治疗即预防[TasP])，在覆盖面方面明显不足，重要的是， 在KAPS中得到充分实施。除了艾滋病毒预防的次优实施外，格鲁吉亚的能力 由于缺乏生物统计学方面的专业知识，控制其疫情的努力一直受到阻碍。这种专业知识不仅需要 分析丰富的数据库阵列，以实时指导更有效的实施，但要以其能力为限 严格设计、实施和分析来自实施试验的数据，这些数据是 在格鲁吉亚的背景下，疫情集中在卡普斯，污名和歧视比比皆是。 为了满足这一需要，我们提议发展格鲁吉亚执行科学福格蒂并使之制度化。 与佐治亚州领先的研究机构伊利亚州立大学(ISU)合作实施培训(GIFT)计划 耶鲁大学。Gift将利用耶鲁大学(医学和公共卫生)的联合资源 与执行支助股合作，提供长期、中期和短期培训。GIFT将通过以下方式专注于艾滋病毒预防 生物统计学和实施研究方法方面的高级培训。具体地说，Gift坚持三个核心 目标包括：1)在一年级培训4名资优教师，然后在二年级和三年级招聘6名博士生， 世卫组织将把培训重点放在艾滋病毒预防上，谁将接受生物统计和 通过混合学习方案实施研究方法；2)传授知识和建设能力 在执行支助股内部，高加索、东欧和中亚通过夏季短期培训 训练营；和3)发展艾滋病毒实施科学和生物统计方法资源中心，以 整合资源，建立伙伴关系，争取更好的人口成果。所有博士生将结对 与ISU和耶鲁大学的导师合作，并获得从艾滋病毒实施试验中分析数据的实际经验 耶鲁大学正在进行或已完成。培训资源将针对格鲁吉亚的艾滋病毒流行情况而定。 以Fogarty培训计划和现有的成功合作经验为基础， 耶鲁大学和ISU之间的伙伴关系，我们准备培训更多的下一代公共卫生研究人员 有效地，认识到需要在卡帕斯更好地实施艾滋病毒预防。礼物将提供 高级培训，以分阶段地将知识、技能和专业知识从耶鲁转移到执行支助股 五年的课程，导致格鲁吉亚顶尖研究型大学的培训示范课程，具有强大的 地区和当地教师的支持以及社区、政府和国际伙伴关系的承诺。