课题基金 / 基金详情

Induction and Inhibition of IgE-Mediated Hypersensitivity to Vaccines

Induction and Inhibition of IgE-Mediated Hypersensitivity to Vaccines
IgE 介导的疫苗超敏反应的诱导和抑制
批准号：
7592344
负责人：
Calman Prussin
金额：
$21.9万
依托单位：
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/7592344
关键词：
AllergicAnaphylaxisAntigensCD4 Positive T LymphocytesClinicalDetectionExtrinsic asthmaFrequenciesFutureGoalsIgEImmediate hypersensitivityImmune responseIndividualInfectious AgentInfluenzaInterferon Type IIInterleukin-4Interleukin-5LifeMeasuresMediatingMedicinePatientsPrimary Health CarePublic HealthT-Cell ProliferationT-LymphocyteTechniquesVaccine AntigenVaccinescytokineresponsetoolvaccine delivery

项目摘要

项目成果

Calman Prussin的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
We examined the question of whether atopic patients with allergic asthma have a quantitatively different immune response to vaccines than do non-atopic control subjects. We determined the frequency and cytokine profile of influenza antigen specific T cells in allergic asthmatic and non-allergic control subjects. No significant differences between the groups were seen in either the individual cytokines (IL-4, IFN-gamma, IL-5), the ratio of IL-4:IFN-gamma, or in CD4 T cell proliferation. These results indicate that using available techniques for detection of antigen specific responses, T cell cytokine responses to influenza do not differ markedly between atopic and non-atopic individuals.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Developmental Immunotherapeutics For Allergic Diseases And Asthma
Highly differentiated IL5+ Th2 cells in food allergy and eosinophilic GI disease
Developmental Immunotherapeutics For Allergic Diseases A
Functional and Epigenetic Analysis of Th2 Heterogeneity
海外基金