NMR facilities to support synthetic chemistry in Nottingham

核磁共振（NMR）光谱是现代化学的基础，因为它是识别新化学物质的基本技术。拟议的新核磁共振设施将支持化学前沿的研究，从化学生物学及其与医学的界面，到当代有机和无机化学，再到新材料。特别是，该设备将支持催化和方法学，天然生物活性化合物的合成，配位化学（包括含金属酶），药物化学（新型酶抑制剂作为治疗剂）和化学生物学（细胞信号传导途径的化学探针）的新项目。具体目标包括模仿自然组装这些分子的方式的天然产物的新途径，药物-DNA相互作用和RNA相互作用分子的研究，从废物流中提取金属盐，纳米结构及其在材料和电子学中的应用，用于气体储存的聚合物，以及木质素（丰富的原材料）的利用。

Nuclear magnetic resonance (NMR) spectroscopy is fundamental to much of modern chemistry for it is an essential technique for identifying new chemical substances. The proposed new NMR facilities will support research at the cutting edge of chemistry in areas ranging from chemical biology and its interface with medicine, through contemporary organic and inorganic chemistry, to new materials. In particular, the equipment will support new projects in catalysis and methodology, the synthesis of naturally occurring bioactive compounds, coordination chemistry including metal-containing enzymes, medicinal chemistry (novel enzyme inhibitors as therapeutic agents) and chemical biology (chemical probes for cellular signaling pathways). Specific goals include new routes to natural products that mimic the ways that Nature assembles such molecules, the study of drug-DNA interactions and RNA-interactive molecules, the extraction of metal salts from waste streams, nanostructures and their applications in materials and electronics, polymers for gas storage, and the utilisation of lignin (a plentiful raw material).