Research in Perinatal Medicine

描述（由申请人提供）：项目摘要：这个博士后计划的目标，自1977年成立以来，一直是提供发育医学家和其他有兴趣的人与必要的技能，一个成功的学术生涯。虽然在美国有许多围产期医学的临床培训计划，但很少有提供发育生物学的强化实验室经验，或临床研究和流行病学的结构化培训。耶鲁大学的临床和基础科学部门都参与了该计划，包括儿科学，内科学，遗传学，病理学，细胞和分子生理学，神经生物学，免疫生物学和流行病学。这些部门的广泛资源可供受训者使用，新生儿特别护理股的设施也是如此，这是耶鲁-纽黑文儿童医院的一个有51个床位的三级护理股。对于选择密集的实验室研究经验的学员，可以在细胞生物学，分子生物学和遗传学方面进行结构化课程。选择从事临床研究的受训人员参加临床试验设计、统计学和流行病学课程。他们也可能成为耶鲁大学公共卫生学院公共卫生硕士学位或调查医学博士学位的候选人。该项目支持4名博士后学员。学员被任命为3年，必须致力于追求学术医学的职业生涯。MD学员将在进入该计划之前完成他们的居住。博士毕业生将对发育生物学表现出兴趣。经过一段适应期后，受训者选择一名导师和一个研究项目。在导师的直接监督下，他们设计，执行，解释和报告他们的研究。由于3年的时间一般不足以建立独立的研究生涯，因此鼓励和协助学员申请资助，以延长他们的研究培训，许多人成功地做到了这一点。该计划的毕业生，现已运作超过28年，在美国各地担任学术职务。许多人已经成为围产期医学和研究的领导者。相关性：医生科学家为生物医学研究及其翻译带来了独特的视角。人们已经认识到，全国缺乏受过适当培训的医学科学家。该方案的持续目标是培训下一代围产期调查人员。

DESCRIPTION (provided by applicant): Project Summary: The goal of this postdoctoral program, since its inception in 1977, has been to provide neonatologists and others interested in developmental medicine with the skills necessary for a successful academic career. Although there are many clinical training programs in neonatal-perinatal medicine in the United States, few offer either an intensive laboratory experience in developmental biology, or structured training in clinical research and epidemiology. Both clinical and basic science departments at Yale University are involved with the program including Pediatrics, Internal Medicine, Genetics, Pathology, Cellular and Molecular Physiology, Neurobiology, Immunobiology and Epidemiology. The extensive resources of these departments are available to trainees as are the facilities of the Newborn Special Care Unit, a 51 bed tertiary care unit in the Yale-New Haven Children's Hospital. For the trainees who choose an intensive laboratory based research experience, structured course work is available in cell biology, molecular biology and genetics. Trainees who elect to do clinical research attend courses in design of clinical trials, statistics and epidemiology. They may also become candidates for the MPH degree at the Yale School of Public Health or the PhD in Investigative Medicine. This program supports 4 postdoctoral trainees. Trainees are appointed for 3 years and must be committed to pursuing a career in academic medicine. MD trainees will have completed their residency prior to entering the program. PhD graduates will have a demonstrated interest in developmental biology. After an orientation period, trainees select a preceptor and a research project. Under the direct supervision of the preceptor, they design, execute, interpret and report their research. Since 3 years are generally insufficient to establish an independent research career, trainees are encouraged and assisted to apply for funding to extend their research training, and many have done so successfully. Graduates of this program, which has now been functioning for over 28 years, hold academic positions throughout the United States. Many have become leaders in perinatal medicine and research. Relevance: Physician-scientists bring a unique perspective to biomedical research and its translation. It has been recognized that there is a national shortage of suitably trained physician-scientists. The ongoing objective of this program is to train members of the next generation of perinatal investigators.