Yale Cooperative Hematology Specialized Core Center

 描述（由申请人提供）：耶鲁合作血液学专业核心中心（YCHSCC）耶鲁合作血液学专业核心中心的目的是促进和加强血液学研究，通过性能和教学为基础的方法为研究人员提供最先进的技术。我们独特的重点是新兴技术在正常和扰动造血的环境中的应用，在这种环境中，创新的技术进步是共享的，并积极利用血液学研究的进步。YCHSCC的更大目标是在血液病相关的研究支持由其他NIDDK合作血液学专业核心中心提供的综合计划中发挥关键作用，通过提供机会与耶鲁大学和其他机构的血液学研究人员增加互动和合作，以及促进早期职业科学家的血液学研究。在YCHSCC中，四个新兴技术研究核心，细胞制备和分析核心，成像核心，表达和基因组学核心以及动物建模核心为血液学研究人员提供最先进技术的访问和帮助。每个新兴技术核心都有详细的教育和培训计划。这些核心还评估和优化新的和新兴的技术，为潜在的血液学为基础的应用。为内部和外部血液学研究者制定了核心访问计划，以及促进早期研究者访问的计划。TE核心的基础设施，加上收费的成本回收系统，在预算不变的情况下运作，将对调查人员有利。丰富计划为血液学研究者提供了机会，通过促进在多个论坛上的信息交流来提高他们的科学知识，这些论坛包括交互式技术共享研讨会、研究进展报告和学员交流计划。试点和可行性计划通过支持早期职业研究者的工作来促进血液学研究，建立血液学新的研究者，以及建立追求新研究目标的血液学研究者。一个行政核心促进YCHSCC的运作，包括履行行政、财务和人事相关职能。对血液学研究者的教育和培训是YCHSCC不可或缺的职能。充分利用耶鲁大学丰富的环境，一个参与，协作的血液学研究基地，以及新兴技术的专业知识，YCHSCC将为血液学界提供推动研究进步的重要机会。最终目标是提高血液病的诊断、治疗和预防。

 DESCRIPTION (provided by applicant): Yale Cooperative Hematology Specialized Core Center (YCHSCC) The purpose of the Yale Cooperative Hematology Specialized Core Center is to facilitate and enhance hematology research by providing investigators access to state-of-the-art technologies via both performance and teaching-based approaches. Our unique focus is the application of emerging technologies to normal and perturbed hematopoiesis in an environment in which innovative technical advances are shared and positively leveraged for the advancement of hematologic research. The larger goal of the YCHSCC is to play a key role in the integrated program of hematologic diseases-related research support provided by other NIDDK Cooperative Hematology Specialized Core Centers by providing opportunities to engender increased interactions and collaborations with hematology investigators within Yale and at other institutions as well as to promote hematology research in early career scientists. In the YCHSCC, four Emerging Technology research cores, a Cell Preparation and Analysis Core, an Imaging Core, an Expression and Genomics Core, and an Animal Modeling Core provide hematology investigators access to and assistance with state-of-the art technologies. Detailed education and training programs are in place for each Emerging Technology Core. These cores also evaluate and optimize new and emerging technologies for potential hematology-based applications. A program for Core access is in place for both internal and external hematology investigators, as is a plan to facilitate access by early stage investigators. Infrastructure for te cores, with fee-based cost recovery systems in place for operation at budget neutrality, will be financially advantageous for investigators. An Enrichment Program provides opportunities for hematology investigators to enhance their scientific knowledge by facilitating the exchange of information in several forums including interactive technique sharing symposia, research in progress presentations, and trainee exchange programs. A Pilot and Feasibility Program promotes hematology research by supporting work of early career investigators, established investigators new to hematology, and established hematology investigators pursuing novel research objectives. An Administrative Core facilitates operations of the YCHSCC, including performing administrative, financial, and personnel-related functions. Education and training of hematology investigators are integral functions of the YCHSCC. Fully active, leveraging the rich environment of Yale University, an engaged, collaborative hematology research base, and expertise in emerging technologies, the YCHSCC will provide the hematology community significant opportunities to drive advances in research. The ultimate goal is to improve diagnosis, treatment, and prevention of hematologic disease.