Yale Cooperative Hematology Specialized Core Center

耶鲁大学合作血液学专业核心中心

• 批准号: 9987207
• 负责人: PATRICK G GALLAGHER
• 金额: $ 2万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-01 至 2020-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9987207
• 关键词: Anatomy; Animal Model; Area; Bioinformatics; Biomedical Research; Blood Cells; Budgets; Cell Communication; Cells; Cellular biology; Collaborations; Communities; Core Facility; Country; Diagnosis; Educational process of instructing; Emerging Technologies; Environment; Faculty; Fees; Funding; Gene Expression; Gene Proteins; Genomics; Goals; Hematological Disease; Hematology; Hematopoiesis; Hematopoietic stem cells; Human Resources; Image; Infrastructure; Institution; Knowledge; Learning; Molecular; National Institute of Diabetes and Digestive and Kidney Diseases; Non-Malignant; Performance; Play; Prevention; Process; Recovery; Regulation; Research; Research Personnel; Research Support; Resources; Role; Scientist; Signal Transduction; System; Techniques; Technology; Testing; Training; Training Programs; Training and Education; Universities; Work; base; career; cell preparation; cost; cost effectiveness; gene function; genome-wide; hematopoietic stem cell self-renewal; improved; innovation; interest; medical schools; member; new technology; novel; operation; progenitor; programs; public health relevance; stem cell biology; symposium; synergism

 DESCRIPTION (provided by applicant): Yale Cooperative Hematology Specialized Core Center (YCHSCC) The purpose of the Yale Cooperative Hematology Specialized Core Center is to facilitate and enhance hematology research by providing investigators access to state-of-the-art technologies via both performance and teaching-based approaches. Our unique focus is the application of emerging technologies to normal and perturbed hematopoiesis in an environment in which innovative technical advances are shared and positively leveraged for the advancement of hematologic research. The larger goal of the YCHSCC is to play a key role in the integrated program of hematologic diseases-related research support provided by other NIDDK Cooperative Hematology Specialized Core Centers by providing opportunities to engender increased interactions and collaborations with hematology investigators within Yale and at other institutions as well as to promote hematology research in early career scientists. In the YCHSCC, four Emerging Technology research cores, a Cell Preparation and Analysis Core, an Imaging Core, an Expression and Genomics Core, and an Animal Modeling Core provide hematology investigators access to and assistance with state-of-the art technologies. Detailed education and training programs are in place for each Emerging Technology Core. These cores also evaluate and optimize new and emerging technologies for potential hematology-based applications. A program for Core access is in place for both internal and external hematology investigators, as is a plan to facilitate access by early stage investigators. Infrastructure for te cores, with fee-based cost recovery systems in place for operation at budget neutrality, will be financially advantageous for investigators. An Enrichment Program provides opportunities for hematology investigators to enhance their scientific knowledge by facilitating the exchange of information in several forums including interactive technique sharing symposia, research in progress presentations, and trainee exchange programs. A Pilot and Feasibility Program promotes hematology research by supporting work of early career investigators, established investigators new to hematology, and established hematology investigators pursuing novel research objectives. An Administrative Core facilitates operations of the YCHSCC, including performing administrative, financial, and personnel-related functions. Education and training of hematology investigators are integral functions of the YCHSCC. Fully active, leveraging the rich environment of Yale University, an engaged, collaborative hematology research base, and expertise in emerging technologies, the YCHSCC will provide the hematology community significant opportunities to drive advances in research. The ultimate goal is to improve diagnosis, treatment, and prevention of hematologic disease.

 描述（由申请人提供）：耶鲁大学合作血液学专业核心中心 (YCHSCC) 耶鲁大学合作血液学专业核心中心的目的是通过基于绩效和教学的方法为研究人员提供最先进的技术，从而促进和加强血液学研究。我们独特的重点是在共享创新技术进步并积极利用其促进血液学研究进步的环境中，将新兴技术应用于正常和紊乱的造血。 YCHSCC 的更大目标是在由其他 NIDDK 合作血液学专业核心中心提供的血液学疾病相关研究支持综合计划中发挥关键作用，提供机会与耶鲁大学和其他机构的血液学研究人员加强互动和合作，并促进早期职业科学家的血液学研究。在 YCHSCC，四个新兴技术研究核心（细胞制备和分析核心、成像核心、表达和基因组学核心以及动物建模核心）为血液学研究人员提供了获得最先进技术的机会和帮助。每个新兴技术核心都有详细的教育和培训计划。这些核心还评估和优化新兴技术，以实现潜在的基于血液学的应用。为内部和外部血液学研究人员制定了核心访问计划，并制定了一项促进早期研究人员访问的计划。技术核心的基础设施，以及在预算中立的情况下运行的收费成本回收系统，将为调查人员带来经济上的优势。丰富项目为血液学研究人员提供了通过促进多个论坛中的信息交流（包括互动技术共享研讨会、进展研究演示和实习生交流项目）来增强其科学知识的机会。试点和可行性计划通过支持早期职业研究者、血液学新研究者以及追求新研究目标的成熟血液学研究者的工作来促进血液学研究。行政核心促进 YCHSCC 的运营，包括履行行政、财务和人事相关职能。血液学研究者的教育和培训是 YCHSCC 的重要职能。 YCHSCC 充分活跃，利用耶鲁大学丰富的环境、积极参与的血液学研究基地以及新兴技术的专业知识，将为血液学界提供推动研究进步的重要机会。最终目标是改善血液疾病的诊断、治疗和预防。