Training Program in Basic and Clinical Communication Science

描述(由申请人提供)：这是一个修订的-A2-培训计划的申请，以寻求资金支持医科学生，耳鼻咽喉科住院医生，研究生和博士后实习生，在基础和临床科学相结合，这是为沟通障碍相关的科学量身定做的。该培训计划的目标是培养出一种新型的临床科学家，他们准备交流想法、专业知识和技术，从而直接有效地将基础科学发现转化为临床测试和应用。此外，这样的临床科学家将有能力产生来自临床研究的机械性假说，这些假说可以直接在基础细胞水平上进行测试。第二个目标是培养新的博士和博士后科学家，他们不仅能够建立独立的研究计划，而且善于识别相关的基础科学问题，并将其整合到与临床相关的答案和解决方案中。这将通过将基本的博士后和博士后研究员同化到一个“教义”培训计划中来实现。该培训计划将在耳鼻咽喉科传播科学计划的赞助下进行，该计划吸引了来自5所学校和12个系的43名教职员工(28名小学成员和15名准成员)，使其成为一个多学科计划。培训者从外部资助了研究项目，这些项目纳入了从行为、系统、细胞/分子生物学、生物化学、生理学和使用动物模型(例如线虫、灵长类)和人类进行的翻译研究等方法。这些培训师的主要研究重点是感觉和交流科学以及精神障碍。拟议的培训计划将通过正式的课程工作得到加强，这些课程将侧重于：1)通信科学，2)暑期学校，3)从工作台到床边的“教义”，4)生物统计学和流行病学，包括临床研究设计，5)生物伦理学，6)分子生物学和遗传学，重点是人类遗传学和疾病，7)口头陈述技能，8)助学金和手稿写作策略，9)了解与职业有关的问题。此外，培训计划还将主办年度务虚会和杰出议长研讨会。为2.5名受训人员申请资金。该机构的承诺将涵盖1.5名学员，以确保基础和临床转化科学项目的平衡，该项目由每年4名学员组成。

DESCRIPTION (provided by applicant): This is a revised - A2 - application for a training program to seek funding support for medical students, ENT residents, graduate and postdoctoral trainees in a blend of basic and clinical science, which is tailored towards the science related to communicative disorders. The goal of this training program is to produce a new type of clinician scientist who is poised to exchange ideas, expertise, and techniques leading to the direct and effective flow and translation of basic-science discoveries into clinical testing and applications. In addition, such a clinical scientist will have the ability to generate mechanistic hypotheses that are derived from clinical research, which can be tested directly at the basic cellular level. The second objective is to produce new PhDs and postdoctoral scientists, who are not only capable of establishing independent research programs, but are also adept at recognizing and integrating relevant basic-science problems into clinically germane answers and solutions. This will be done by assimilating basic pre- and postdoctoral fellows, into a "doctrine" training program. The training plan will operate under the auspices of the Communication Science Program in the Department of Otolaryngology, which draws 43 faculty (28 primary and 15 associate members) from 5 schools and 12 departments making it a multidisciplinary program. The trainers have extramurally funded research programs that incorporate approaches ranging from behavior, systems, cellular/molecular biology, biochemistry, physiology and translational research using animal models (e.g., C. elegans, primates) and humans. The primary research emphasis of these trainers is on sensory and communication sciences and disorders. The proposed training program will be enhanced with formal course work that will focus on: 1) communication science, 2) summer schools, 3) "doctrine" from bench to bedside, 4) biostatistics and epidemiology including clinical-study design, 5) bioethics, 6) molecular biology and genetics, with emphasis on human genetics and diseases, 7) oral presentations skills, 8) grant and manuscript writing strategies, and 9) understanding career-related issues. In addition, the training program will sponsor an annual retreat and Distinguished Speaker Seminars. Funds for 2.5 trainees are requested. The institution commitment will cover 1.5 trainees to ensure a balance of a basic and clinical translational science program consisting of 4 trainees per year.