21st-Century Imaging Sciences: Undergraduate and Graduate Student Training

描述（由申请人提供）：影像科学持续发展的关键是整合传统的离散研究线。例如，观察活细胞中的细胞器和大分子复合物的进展需要与活体动物成像的新方法方法相结合；产生新型显像剂的生物化学进展需要与选择性细胞递送的新方法相结合，并采用模拟人类疾病的转基因动物模型。为了实现分子、细胞、活体动物和人类成像不断发展的范式所提供的潜力，必须培养一批21世纪的科学家骨干，并且必须实现化学、生物学、工程学、物理学和数学的革命性综合。华盛顿大学的成像科学界，由于其广度、多样性和资金的深度，在通过吸引和培训下一代成像科学家来促进新方法的发展方面处于有利地位。我们建议在学生学术生涯的最重要阶段，即本科和研究生阶段，设计课程并开发机会。早期接触学生对于在物理和生命科学以及工程方面建立广泛的学术基础是必不可少的。将开设本科影像科学课程。大三和大四的学生将有机会学习与成像科学相关的化学、物理、计算机科学、工程和分子细胞生物学课程，并在成像科学学院的实验室获得深入的研究经验。对于博士预科生，我们建议为生物医学科学、物理和定量科学、心理学和工程学的学生创建一个研究生成像科学途径。我们预计，到2008年，研究生衔接课程将成熟为正式的研究生课程，届时我们将优化课程设置，并开发出跨学科培训的管理机制，由文理学院、医学院、工程与应用科学学院的导师指导学生。我们设想，完成成像科学途径或研究生课程培训的研究生将准备拓宽他们的视野，并为跨学科科学的新时代开辟新的研究机会。相关机构：NIBIB， NIGMS， NCI， NINDS, NHLBl

DESCRIPTION (provided by applicant): Critical to continued progress in imaging sciences is the integration of traditionally discrete lines of research. For example, advances in observing organelles and macromolecular complexes in living cells need to be integrated with new methodological approaches to imaging live animals; advances in biochemistry that produce novel imaging agents need to be integrated with new approaches to selective cellular delivery and employ transgenic animal models simulating human diseases. To realize the potential that evolving paradigms of molecular, cellular, live animal and human imaging offer, a cadre of 21st-century scientists must be trained-and a revolutionary synthesis of chemistry, biology, engineering, physics and mathematics must be achieved. The imaging science community at Washington University, because of its breadth, diversity and depth of funding, is in an excellent position to foster the development of a new approach by attracting and training next-generation imaging scientists. We propose to devise curricula and develop opportunities that reach out to students at the most formative stages of their academic careers-in their undergraduate and graduate years. Early access to students is imperative to develop a broadly-based academic foundation in both the physical and life sciences, and in engineering. An Undergraduate Imaging Sciences Pathway will be developed. Students in their junior and senior years will have the opportunity to take courses in chemistry, physics, computer science, engineering and molecular cell biology as they relate to imaging sciences, and to gain in-depth research experience in laboratories of imaging sciences faculty. For predoctoral students, we propose to create a Graduate Imaging Sciences Pathway that will be available to students in the biomedical sciences, physical and quantitative sciences, psychology, and engineering. We anticipate that the Graduate Pathway program will mature into a formal graduate program in 2008, when we have optimized the curriculum and developed the administrative mechanisms for interdisciplinary training of students having mentors in the Schools of Arts and Sciences, Medicine, and Engineering and Applied Sciences. We envision that a graduate student who has completed training in the Imaging Sciences Pathway or graduate program will be poised to broaden their horizons and open new opportunities for research in the new age of interdisciplinary science. [Relevant Institutes: NIBIB, NIGMS, NCI, NINDS, NHLBl