21st-Century Imaging Sciences: Undergraduate and Graduate Student Training

描述（由申请人提供）：在成像科学的持续进步的关键是传统的离散线的研究的整合。例如，在观察活细胞中的细胞器和大分子复合物方面的进展需要与活体动物成像的新方法学方法相结合;在产生新型成像剂的生物化学方面的进展需要与选择性细胞递送的新方法相结合，并采用模拟人类疾病的转基因动物模型。为了实现分子、细胞、活体动物和人类成像的发展模式所提供的潜力，必须培养一批21世纪的科学家，必须实现化学、生物学、工程学、物理学和数学的革命性综合。华盛顿大学的成像科学界，由于其广泛性，多样性和资金的深度，是在一个很好的位置，以促进通过吸引和培训下一代成像科学家的新方法的发展。我们建议设计课程和开发机会，接触到学生在他们的学术生涯的最形成阶段，在他们的本科和研究生年。抢先体验学生对于在物理和生命科学以及工程领域建立广泛的学术基础至关重要。将开发本科成像科学途径。学生在他们的大三和大四将有机会参加化学，物理，计算机科学，工程和分子细胞生物学课程，因为他们涉及到成像科学，并获得深入的研究经验，在成像科学学院的实验室。对于博士前的学生，我们建议创建一个研究生成像科学途径，将提供给学生在生物医学科学，物理和定量科学，心理学和工程。我们预计，研究生衔接课程将在2008年成熟为正式的研究生课程，届时我们已经优化了课程，并制定了跨学科培训学生的管理机制，这些学生在艺术和科学，医学，工程和应用科学学院有导师。我们设想，谁已经完成了在成像科学途径或研究生课程的培训研究生将准备扩大他们的视野，并在跨学科科学的新时代的研究开辟新的机会。[相关机构：NIBIB、NIGMS、NCI、NINDS、NHLB 1

DESCRIPTION (provided by applicant): Critical to continued progress in imaging sciences is the integration of traditionally discrete lines of research. For example, advances in observing organelles and macromolecular complexes in living cells need to be integrated with new methodological approaches to imaging live animals; advances in biochemistry that produce novel imaging agents need to be integrated with new approaches to selective cellular delivery and employ transgenic animal models simulating human diseases. To realize the potential that evolving paradigms of molecular, cellular, live animal and human imaging offer, a cadre of 21st-century scientists must be trained-and a revolutionary synthesis of chemistry, biology, engineering, physics and mathematics must be achieved. The imaging science community at Washington University, because of its breadth, diversity and depth of funding, is in an excellent position to foster the development of a new approach by attracting and training next-generation imaging scientists. We propose to devise curricula and develop opportunities that reach out to students at the most formative stages of their academic careers-in their undergraduate and graduate years. Early access to students is imperative to develop a broadly-based academic foundation in both the physical and life sciences, and in engineering. An Undergraduate Imaging Sciences Pathway will be developed. Students in their junior and senior years will have the opportunity to take courses in chemistry, physics, computer science, engineering and molecular cell biology as they relate to imaging sciences, and to gain in-depth research experience in laboratories of imaging sciences faculty. For predoctoral students, we propose to create a Graduate Imaging Sciences Pathway that will be available to students in the biomedical sciences, physical and quantitative sciences, psychology, and engineering. We anticipate that the Graduate Pathway program will mature into a formal graduate program in 2008, when we have optimized the curriculum and developed the administrative mechanisms for interdisciplinary training of students having mentors in the Schools of Arts and Sciences, Medicine, and Engineering and Applied Sciences. We envision that a graduate student who has completed training in the Imaging Sciences Pathway or graduate program will be poised to broaden their horizons and open new opportunities for research in the new age of interdisciplinary science. [Relevant Institutes: NIBIB, NIGMS, NCI, NINDS, NHLBl