Biostatistics Training with Application to Neuroscience

描述(由申请人提供)： 每个层次的生物医学研究都依赖于概率和统计。如果没有恰当的研究设计和基于健全的统计理论的分析，从研究结果得出的推论和结论将是有偏见的，甚至是无效的。在美国，生物统计师严重短缺，这是因为生物医学研究界对他们的需求日益增长，以及过去几十年来博士水平的生物统计师的毕业率相对稳定。在神经科学领域工作的博士级别的生物统计学家很少。为了在不断扩大的神经科学研究领域保持卓越，必须通过对有兴趣从事学术和研究事业的研究员和学生进行跨学科培训来缓解这种短缺。此外，对神经科学家进行生物统计学方法论方面的教育，将确保他们精通分析技能和欣赏统计投入的坚实基础，从而提高他们的研究质量。南卡罗来纳医科大学(MUSC)生物统计、生物信息学和流行病学系(DBBE)要求为一个致力于神经科学应用(BTAN)的生物统计学培训的教育项目提供资金。该项目将在博士后和博士后阶段对考生进行培训。博士前实习生将获得生物统计学博士学位，从事专注于生物统计学方法论的论文研究，并直接应用于神经科学研究。博士后研究员将是受过临床或基础科学培训的神经科学家，他们将发展与其特定神经科学研究相关的生物统计学方法和技术的广泛应用知识。他们将通过在DBBE成功完成临床研究(临床神经科学家)或生物医学科学(基础神经科学家)的硕士学位课程来实现这一目标。自20世纪70年代初以来，DBBE一直在提供生物统计学的博士和硕士学位课程。它有完善的行政和研究基础设施来容纳和支持BTAN计划。BTAN计划包括生物统计学和神经科学的教学和辅助培训，所有研究项目都专门侧重于将生物统计学应用于神经科学。在将生物统计学应用于神经科学问题方面具有显著优势的DBBE教员与南加州大学神经科学研究所的临床和基础科学教员合作，担任BTAN学员的主要导师，这些教员在各自的神经科学和医学领域担任副导师和专家。

DESCRIPTION (provided by applicant): Biomedical research at every level relies on probability and statistics. Without proper research design and analysis based on sound statistical theory, inferences and conclusions made from the results of the study would be biased and even invalid. In the United States, there is a severe shortage of biostatisticians because of a combination of growing demand for them by the biomedical research community and a relatively steady rate of graduating doctoral level biostatisticians over the last couple of decades. Doctoral level biostatisticians working in the neuroscience field are scarce. In order to maintain excellence in the expanding neuroscience research field, this shortage must be alleviated through interdisciplinary training of fellows and students interested in pursuing academic and research careers. Furthermore, educating neuroscientists in biostatistical methodology will enhance the quality of their research by ensuring a firm foundation of proficiency with analytical skills and appreciation for statistical input. The Department of Biostatistics, Bioinformatics and Epidemiology (DBBE) at the Medical University of South Carolina (MUSC) requests funds for an educational program dedicated to Biostatistics Training with Application to Neuroscience (BTAN). This program will train candidates at both pre- and post-doctoral levels. Pre-doctoral trainees will earn a PhD degree in biostatistics, undertaking dissertation research focused on biostatistical methodology with direct application to neuroscience research. The post-doctoral fellows will be clinically- or basic science-trained neuroscientists who will develop a broad working knowledge of biostatistical approaches and techniques pertinent to their specific neuroscience investigations. They will achieve this through successfully completing a Master's degree program in clinical research (for clinical neuroscientists) or biomedical sciences (basic neuroscientists) in DBBE. DBBE has offered doctoral and master's level degree programs in biostatistics since the early 1970s. It has a well established administrative and research infrastructure to house and support the BTAN Program. The BTAN Program consists of didactic instruction and adjunctive training in both biostatistics and the neurosciences, with all research projects focused specifically on the application of biostatistics to neuroscience. DBBE faculty members with significant strengths in the application of biostatistics to problems in neuroscience serve as primary mentors for the BTAN trainees, in partnership with clinical and basic science faculty in MUSC's Neuroscience Institute, who serve as associate mentors and experts in their respective fields of neuroscience and medicine.