Hybrid optical-electrical stimulation for precise neural stimulation

在世界首创的研究中，我们有证据表明，将电刺激与光刺激相结合显著且安全地提高了耳蜗和视网膜植入物等设备的神经激活精度。在这项提案中，我们将在临床前动物模型中使用基因疗法使神经对光做出反应，以建立概念证据，即混合刺激将显着改善接受人工耳蜗和视网膜植入物的患者的结果。

In world-first research, we have evidence that combining electrical stimulation with optical stimulation significantly and safely improves precision of neural activation for devices such as cochlear and retinal implants. In this proposal we will use gene therapy to make nerves responsive to light in pre-clinical animal models to establish proof of concept that hybrid stimulation will significantly improve outcomes for recipients of cochlear and retinal implants.