Core--Morphometry and Physiology

核心——形态测量与生理学

• 批准号: 7491185
• 负责人: William C Sessa
• 金额: $ 15.87万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-01 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7491185
• 关键词: Arteriosclerosis; Evaluation; In Vitro; Physiological; Physiology; Purpose; Vasomotor; in vivo; morphometry

The purposes of the Morphometry and Physiology Core are to evaluate the morphometric and physiological changes that occur during graft arteriosclerosis (GA) that culminate in constrictive remodeling and to assess the vasomotor function during the progression of GA in vitro. The combination of histological assessment and morphometric evaluation in conjunction with vessel physiology will allow us to dissect when vasomotor function contributes to GA remodeling. This Core will interface with Projects by Pober, Min, and Tellides to assess the degree of remodeling and function in vessels undergoing GA in vivo.

形态学和生理学核心的目的是评估移植物动脉硬化（GA）过程中发生的形态学和生理学变化，最终导致收缩重塑，并评估体外血管舒缩功能。组织评估和形态测量评估结合血管生理学将使我们能够解剖血管舒缩功能何时有助于GA