Health Services Research in Tuberculosis and HIV/AIDS

尽管过去10年来乌干达的艾滋病毒血清阳性反应率有所下降，但艾滋病毒在乌干达的流行远未得到控制。 面对艾滋病毒的流行，结核病发病率很高，死亡率很高。 随着抗逆转录病毒疗法的出现，单靠预防战略已不足以满足乌干达目前的需要。 现在，在道义上必须把艾滋病毒领域的显著进展带给像乌干达这样的发展中国家。 重建乌干达公共卫生基础设施的一个关键步骤是乌干达卫生部、国防部和马凯雷雷大学之间开展独特的合作，成立了联合临床研究中心。 联合研究中心是一个专门研究艾滋病毒的研究和保健机构，在非洲开放抗逆转录病毒疗法方面处于领先地位。 多年来，JCRC与凯斯西储大学（CWRU），国家结核病和麻风病控制计划（NTLP），Makerere和Mbarara大学建立了强有力的合作关系。 拟议的培训计划将建立在这些与控制艾滋病毒和结核病的共同使命的牢固关系的基础上。 该培训方案的目标是通过临床、业务和卫生服务研究，扩大国家能力，以应对乌干达不断演变的艾滋病毒和结核病流行所带来的公共卫生和科学挑战。 通过这一培训方案，乌干达将建设将基础和临床研究成果转化为公共卫生政策和干预措施并评估其有效性的能力。 培训计划将建立在越来越多的艾滋病毒和结核病临床研究项目的基础上，但将把这些研究的结果扩展到公共卫生和政策竞技场。 这些目标将通过与CWRU合作的学位和非学位培训的连贯方案来实现，这将加强乌干达进行与艾滋病毒和结核病有关的综合临床，业务和卫生服务研究的能力。 该计划的研究培训将与乌干达坎帕拉JCRC、UD CWRU、Mbarara科技大学、NTLP、坎帕拉市理事会、CDC、USAID和Elizabeth Glaser儿科基金会正在进行的研究和计划活动相联系。

Although the seroprevalence of HIV has declined in Uganda over the past 10 years, the HIV epidemic in Uganda is far from controlled. In the face of the HIV epidemic, tuberculosis rates are high and associated with significant mortality. With the advent of antiretroviral therapy, prevention strategies alone are no longer sufficient to meet the current needs in Uganda. There is now a moral imperative to bring the remarkable advances in the field of HIV to developing countries like Uganda. One key step in the rebuilding of the Uganda public health infrastructure resulted from a unique collaboration between the Ugandan Ministry of Health, the Ministry of Defense and Makerere University to form the Joint Clinical Research Centre (JCRC). The JCRC is a research and health care facility devoted entirely to HIV and leads the way in opening Africa to antiretroviral therapy. Through the years, the JCRC has formed strong collaborations with Case Western Reserve University (CWRU), the National Tuberculosis and Leprosy Control Programme (NTLP), Makerere and Mbarara University. The proposed training program will build on these strong relationships with the common mission of controlling HIV and TB. The goals of this training program are to expand the national capacity to address the public health and scientific challenges of the evolving HIV and TB epidemic in Uganda through clinical, operational and health services research. Through this training program Uganda will build the capacity to translate basic and clinical research findings into public health policy and interventions, and to evaluate their effectiveness. The training program will build on a growing number of clinical research projects on HIV and TB, but will extend the findings of these studies to the public health and policy arena. The goals will be met through a coherent program of degree and non-degree training in collaboration with CWRU, that will strengthen the capacity in Uganda to conduct integrated clinical, operational and health services research related to HIV and TB. The research training in the program will be linked to the ongoing research and program activities at the JCRC in Kampala, Uganda, CWRU in the UD, Mbarara University of Sciences and Technology, NTLP, Kampala City Council, CDC, USAID and Elizabeth Glaser Pediatric Foundation.