Health Services Research in Tuberculosis and HIV/AIDS

结核病和艾滋病毒/艾滋病卫生服务研究

• 批准号: 7209821
• 负责人: Christopher C. Whalen
• 金额: $ 18.07万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-06-28 至 2009-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7209821
• 关键词: AIDS/HIV problem; Address; Africa; Centers for Disease Control and Prevention (U.S.); Childhood; Cities; Clinical; Clinical Research; Collaborations; Developed Countries; Developing Countries; Effectiveness; Epidemic; Face; Foundations; Goals; HIV; HIV Seroprevalence; Health; Health Policy; Health Services Research; Health care facility; Intervention; Joints; Leprosy; Link; Mission; Morals; Numbers; Prevention strategy; Public Health; Rate; Research; Research Infrastructure; Research Project Grants; Research Training; Science; Technology; Training; Training Programs; Translating; Tuberculosis; USAID; Uganda; Universities; antiretroviral therapy; mortality; programs

Although the seroprevalence of HIV has declined in Uganda over the past 10 years, the HIV epidemic in Uganda is far from controlled. In the face of the HIV epidemic, tuberculosis rates are high and associated with significant mortality. With the advent of antiretroviral therapy, prevention strategies alone are no longer sufficient to meet the current needs in Uganda. There is now a moral imperative to bring the remarkable advances in the field of HIV to developing countries like Uganda. One key step in the rebuilding of the Uganda public health infrastructure resulted from a unique collaboration between the Ugandan Ministry of Health, the Ministry of Defense and Makerere University to form the Joint Clinical Research Centre (JCRC). The JCRC is a research and health care facility devoted entirely to HIV and leads the way in opening Africa to antiretroviral therapy. Through the years, the JCRC has formed strong collaborations with Case Western Reserve University (CWRU), the National Tuberculosis and Leprosy Control Programme (NTLP), Makerere and Mbarara University. The proposed training program will build on these strong relationships with the common mission of controlling HIV and TB. The goals of this training program are to expand the national capacity to address the public health and scientific challenges of the evolving HIV and TB epidemic in Uganda through clinical, operational and health services research. Through this training program Uganda will build the capacity to translate basic and clinical research findings into public health policy and interventions, and to evaluate their effectiveness. The training program will build on a growing number of clinical research projects on HIV and TB, but will extend the findings of these studies to the public health and policy arena. The goals will be met through a coherent program of degree and non-degree training in collaboration with CWRU, that will strengthen the capacity in Uganda to conduct integrated clinical, operational and health services research related to HIV and TB. The research training in the program will be linked to the ongoing research and program activities at the JCRC in Kampala, Uganda, CWRU in the UD, Mbarara University of Sciences and Technology, NTLP, Kampala City Council, CDC, USAID and Elizabeth Glaser Pediatric Foundation.

尽管过去10年来乌干达的艾滋病毒血清患病率有所下降，但乌干达的艾滋病毒疫情远未得到控制。在艾滋病毒流行的情况下，结核病的发病率很高，死亡率很高。随着抗逆转录病毒疗法的出现，仅靠预防战略已不足以满足乌干达目前的需要。现在，将艾滋病毒领域的显著进展带给乌干达等发展中国家在道义上势在必行。