Health Services Research in Tuberculosis and HIV/AIDS

结核病和艾滋病毒/艾滋病卫生服务研究

• 批准号: 7209821
• 负责人: Christopher C. Whalen
• 金额: $ 18.07万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-06-28 至 2009-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7209821
• 关键词: AIDS/HIV problem; Address; Africa; Centers for Disease Control and Prevention (U.S.); Childhood; Cities; Clinical; Clinical Research; Collaborations; Developed Countries; Developing Countries; Effectiveness; Epidemic; Face; Foundations; Goals; HIV; HIV Seroprevalence; Health; Health Policy; Health Services Research; Health care facility; Intervention; Joints; Leprosy; Link; Mission; Morals; Numbers; Prevention strategy; Public Health; Rate; Research; Research Infrastructure; Research Project Grants; Research Training; Science; Technology; Training; Training Programs; Translating; Tuberculosis; USAID; Uganda; Universities; antiretroviral therapy; mortality; programs

Although the seroprevalence of HIV has declined in Uganda over the past 10 years, the HIV epidemic in Uganda is far from controlled. In the face of the HIV epidemic, tuberculosis rates are high and associated with significant mortality. With the advent of antiretroviral therapy, prevention strategies alone are no longer sufficient to meet the current needs in Uganda. There is now a moral imperative to bring the remarkable advances in the field of HIV to developing countries like Uganda. One key step in the rebuilding of the Uganda public health infrastructure resulted from a unique collaboration between the Ugandan Ministry of Health, the Ministry of Defense and Makerere University to form the Joint Clinical Research Centre (JCRC). The JCRC is a research and health care facility devoted entirely to HIV and leads the way in opening Africa to antiretroviral therapy. Through the years, the JCRC has formed strong collaborations with Case Western Reserve University (CWRU), the National Tuberculosis and Leprosy Control Programme (NTLP), Makerere and Mbarara University. The proposed training program will build on these strong relationships with the common mission of controlling HIV and TB. The goals of this training program are to expand the national capacity to address the public health and scientific challenges of the evolving HIV and TB epidemic in Uganda through clinical, operational and health services research. Through this training program Uganda will build the capacity to translate basic and clinical research findings into public health policy and interventions, and to evaluate their effectiveness. The training program will build on a growing number of clinical research projects on HIV and TB, but will extend the findings of these studies to the public health and policy arena. The goals will be met through a coherent program of degree and non-degree training in collaboration with CWRU, that will strengthen the capacity in Uganda to conduct integrated clinical, operational and health services research related to HIV and TB. The research training in the program will be linked to the ongoing research and program activities at the JCRC in Kampala, Uganda, CWRU in the UD, Mbarara University of Sciences and Technology, NTLP, Kampala City Council, CDC, USAID and Elizabeth Glaser Pediatric Foundation.

尽管乌干达的艾滋病毒血清阳性率在过去10年中有所下降，但乌干达的艾滋病毒疫情远未得到控制。在艾滋病毒流行的情况下，结核病发病率很高，而且死亡率很高。随着抗逆转录病毒疗法的出现，单靠预防战略已不足以满足乌干达目前的需要。现在有一种道德上的当务之急，把艾滋病毒领域的显着进步带给像乌干达这样的发展中国家。 重建乌干达公共卫生基础设施的一个关键步骤是乌干达卫生部、国防部和Makerere大学之间独特的合作，成立了联合临床研究中心(JCRC)。JCRC是一个完全致力于艾滋病毒的研究和保健机构，在向非洲开放抗逆转录病毒治疗方面走在了前列。多年来，JCRC与凯斯西储大学(CWRU)、国家结核病和麻风病控制方案(NTLP)、Makerere和Mbarara大学建立了强有力的合作关系。拟议的培训计划将建立在与控制艾滋病毒和结核病的共同使命的这些牢固关系的基础上。 这一培训计划的目标是通过临床、业务和卫生服务研究，扩大国家能力，以应对乌干达不断发展的艾滋病毒和结核病疫情带来的公共卫生和科学挑战。通过这一培训方案，乌干达将建设将基础和临床研究成果转化为公共卫生政策和干预措施并评估其有效性的能力。该培训计划将建立在越来越多的艾滋病毒和结核病临床研究项目的基础上，但将把这些研究的结果扩展到公共卫生和政策领域。这些目标将通过与CWRU合作的学位和非学位培训的连贯计划来实现，该计划将加强乌干达开展与艾滋病毒和结核病有关的综合临床、业务和卫生服务研究的能力。该计划中的研究培训将与乌干达坎帕拉的JCRC、UD的CWRU、姆巴拉拉科技大学、NTLP、坎帕拉市议会、疾控中心、美国国际开发署和伊丽莎白·格拉泽儿科基金会正在进行的研究和计划活动联系起来。