BIOSTATISTICS CORE

生物统计学核心

• 批准号: 7300577
• 负责人: Steven N. Goodman
• 金额: $ 19.35万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-06-01 至 2012-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7300577
• 关键词: Area; Arts; Bioinformatics; Biological; Biometry; Biostatistics Core; Books; Breast; Clinical; Clinical Sciences; Clinical Trials; Clinical Trials Design; Collaborations; Collection; Commit; Complex; Consultations; Data; Data Analyses; Data Collection; Data Storage and Retrieval; Detection; Development; Ensure; Equipment; Experimental Designs; Faculty; Fertilization; Funding; Genomics; Head and neck structure; Housing; Human Resources; Imagery; Informatics; Information Storage; K-Series Research Career Programs; Logistics; Manuscripts; Methodology; Modeling; Morphologic artifacts; Phase; Positioning Attribute; Procedures; Publishing; Quality Control; Range; Recording of previous events; Reproduction spores; Research; Research Design; Research Personnel; Resources; Risk Marker; Running; Solutions; Specialist; Techniques; Technology; Testing; Work; Writing; computerized data processing; data acquisition; data management; design; experience; genetic epidemiology; innovation; interest; longitudinal animal study; member; oncology; programs; quality assurance; stem; success; tool

This Core resource will provide comprehensive biostatistics and bioinformatics consultation and collaboration to all projects in the proposed Johns Hopkins Head and Neck SPORE. In addition, it will provide support for data storage, informatics, and computing, and assist with the identification and solution of complex data tasks arising in the course of project activities. Core members will work with project investigators across a wide spectrum of activities, encompassing data acquisition (including study design, feasibility of objectives, availability of public-access genomic information, and data storage), statistical quality control (including artifact detection and preprocessing of data from genomic technologies), data analysis (including visualization, biostatistical modeling, and assistance with manuscript writing), and development of innovative customized biostatistics and bioinformatics methodologies and tools if required by specific projects. The proposed Head and Neck SPORE Biostatistics Core will be housed in the Division of Clinical Trials and Biometry of the Department of Oncology, an active and committed group of biostatistics and bioinformatics faculty members, with access to state-of-the art equipment and a broad range of expertise. This Core resource is the continuation of an existing resource within the original and current Head and Neck SPORE program at Johns Hopkins. Core members have a strong commitment to this SPORE, stemming from: a) a history of collaboration with the investigators of this as well as other SPORE projects, b) an active and independently funded agenda of synergistic projects, and c) a demonstrated interest and understanding of both the biological and analytical questions and challenges. All proposed projects are anticipated to make use of this resource.

该核心资源将提供全面的生物统计学和生物信息学咨询与合作 约翰·霍普金斯头颈孢子计划中的所有项目。此外，它将提供支持 数据存储、信息学和计算，协助复杂数据的识别和解决 项目活动过程中出现的任务。核心成员将与项目研究人员合作 广泛的活动，包括数据采集（包括研究设计、目标的可行性、 公共获取基因组信息和数据存储的可用性）、统计质量控制（包括 来自基因组技术的伪影检测和数据预处理）、数据分析（包括 可视化、生物统计建模以及手稿写作协助）以及创新开发 如果特定项目需要，定制生物统计学和生物信息学方法和工具。这 拟议的头颈 SPORE 生物统计核心将设在临床试验和 肿瘤科的生物计量学，一个活跃且专注的生物统计学和生物信息学小组 教职员工拥有最先进的设备和广泛的专业知识。这个核心 资源是原始和当前 Head and Neck SPORE 中现有资源的延续 约翰·霍普金斯大学的计划。核心成员对此 SPORE 有着坚定的承诺，源于：a) 与该项目以及其他 SPORE 项目的研究人员的合作历史，b) 积极且 独立资助的协同项目议程，以及 c) 表现出的兴趣和理解 生物学和分析问题和挑战。所有拟议项目预计将 使用该资源。