Child Health Research Career Development Award

描述（由申请人提供）：哥伦布儿童医院儿童健康研究中心职业发展奖（CHRCDA）的长期目标是培养新一代儿科实验室科学家，该奖项位于俄亥俄州州立大学医学院儿科系。对于这次更新申请，我们继续我们现有的CHRCDA的主题，即儿科的分子医学。在精心挑选的，经验丰富的专职导师的指导下，我们建议继续培训最高素质的儿科医生学者，准备承担分子医学的最新进展预防和治疗儿童疾病。在CHRCDA的9年生命周期中，我们已将学者转变为独立的联邦资助，其资助率高于全国同行CHRCDA机构的平均水平。我们的学员已经出版了118篇学术出版物，82%留在学术界。一位学者是代表性不足的少数群体。45%是妇女，超过了全国平均水平。在此成功记录的基础上，在当前的应用中，我们扩大了经验丰富的调查员/导师队伍，并提出了一个独特的强化指导计划，远远超出了提供动手实验室经验的范围。正式的教学和小组计划在人类疾病的生物学，实验设计，granecomp和研究伦理提供支持学者的过渡到独立。CHRCDA由一名主要研究员、一名项目主任、一名招聘人员以及内部和外部专家咨询委员会监督。27名基础实验室科学家热情地同意担任导师。哥伦布儿童研究所的研究环境从未如此强大，计划在2005年至2010年期间投资2亿美元用于研究项目和基础设施。儿科奖学金计划继续在我们的机构和外部候选人的招聘继续快速增长，确保人才的持续管道，从中招募学者。因此，我们处于理想的位置，以延长我们的成功CHRCDA的额外间隔的支持。

DESCRIPTION (provided by applicant): The long-term objective of the Columbus Children's Hospital Child Health Research Center Career Development Award (CHRCDA), based in the Department of Pediatrics at The Ohio State University College of Medicine, is to train a new generation of pediatric laboratory scientists. For this renewal application, we continue the theme of our existing CHRCDA, that is, molecular medicine in pediatrics. Under the guidance of a carefully selected, experienced faculty of dedicated mentors, we propose to continue training pediatric physician scholars of the highest caliber, poised to bring to bear the latest advances in molecular medicine on the prevention and healing of childhood disease. Over the 9 year lifetime of our CHRCDA, we have transitioned scholars to independent federal funding at a rate above the national average for peer CHRCDA institutions. Our trainees have published 118 scholarly publications and 82% remain in academia. One scholar has been an underrepresented minority. Forty-five percent have been women, exceeding the national average. Building on this record of success, in the current application we have expanded our cadre of Experienced Investigators/Mentors and propose a unique, intensified mentoring program that extends far beyond provision of a hands-on laboratory experience. Formal didactic and small group programs in the biology of human disease, experimental design, grantsmanship, and research ethics are offered in support of transition of scholars to independence. The CHRCDA is overseen by a Principal Investigator, a Program Director, a Recruiter, and expert internal and external advisory committees. Twenty seven basic laboratory scientists have enthusiastically agreed to serve as mentors. The research environment at Columbus Children's Research Institute has never been stronger, with a $200 million investment in research programs and infrastructure planned between 2005 and 2010. Pediatric fellowship programs continue to grow at our institution and recruitment of external candidates continues apace, ensuring an ongoing pipeline of talent from which to recruit scholars. Thus, we are ideally positioned to extend our successful CHRCDA for an additional interval of support.