Child Health Research Career Development Award

首席研究员/项目主管（最后，第一，中间）：Hansen, Thomas N.描述：说明申请的广泛，长期目标和具体目标，并参考项目的健康相关性。简要描述为实现这些目标的研究设计和方法。避免总结过去的成就和使用第一人称。当与应用程序分离时，这个抽象意味着作为提议工作的简洁和准确的描述。如果该应用程序获得资助，则此描述将成为公开信息。因此，不要包含专有/保密信息。不要超出空间范围。哥伦布儿童医院儿童健康研究职业奖（CCH-CHRCDA）的长期目标是培养新的儿科医生科学家。由于过去十年生物医学科学的迅速发展，迫切需要加快将基础科学发现转化为有利于儿童健康的临床应用。作为俄亥俄州立大学（Ohio State University）一家专门从事儿童护理（CCH）的医院的大型多学科儿科，我们处于推动这一事业的理想位置。我们将继续我们现有的CHRC的主题，这一竞争更新应用-儿科分子医学。虽然科学和医学自1996年首次申请以来发展迅速，但我们选择的主题的基本前提只是得到了验证。我们为过去四年取得的成就感到自豪。我们的前3位CHRC学者都连续获得了独立的NIH R01资助。包括我们目前接受CHRC资助的3位学者在内，50%（3/6）是女性，17%（1/6）是少数民族（非洲人）。机构对研究和CHRC的支持从未如此强大。在过去的五年中，CCH通过儿童研究所和该部门投资了超过2000万美元来扩大研究。去年，CCH承诺进一步扩大设施和师资队伍。因此，我们准备扩展我们成功的CHRC计划。我们精心挑选了来自儿童研究所和俄亥俄州立大学6个系、3个学院和3个研究所的21名资深教师作为既定调查员。此外，我们已经确定了一个优秀的潜在学者池为这个续签申请。网站性能 ======================================== 节结束 ===========================================

Principal Investigator/Program Director (Last, first, middle): Hansen, Thomas N. DESCRIPTION: State the application'sbroad, long-term objectivesand specificaims, makingreference to the healthrelatednessof the project.Descdbe concisely the research designand methodsfor achievingthese goals.Avoid summariesof past accomplishmentsand the use of the first person.Thisabstractis meant to serve as a succinctand accurate descriptionof the proposedworkwhen separatedfrom the application.Ifthe applicationis funded,thisdescription,as is,will become pub_'licnformation.Therefore, do not includeproprietary/confidentiainl formation.DO NOT EXCEE¿) 3'HE SPACE PRO_/_DE_. The long-term objective of Columbus Children's Hospital Child Health Research Career Award (CCH-CHRCDA) is to train new pediatric physician-scientists. Because of rapid advances in biomedical sciences during the past decade, there is a pressing need to speed the transfer of basic science discoveries to clinical applications that will benefit the health of children. As a large, multidisciplinary Department of Pediatrics (Ohio State University) at a hospital devoted solely to the care of children (CCH), we are ideally positioned to further this cause. We will continue the theme of our existing CHRC for this competing renewal application - molecular medicine in pediatrics. Although science and medicine have moved forward at a rapid pace since our original application in 1996, the basic premise of our chosen theme has only gained validation. We are proud of our achievements over the last 4 years. Our first 3 CHRC Scholars have all in succession obtained independent NIH R01 funding. Including our 3 Scholars currently receiving CHRC funding, 50% (3/6) have been wonaen and 17% (1/6) have been minorities (African). Institutional support of research and the CHRC has never been stronger. Over the past 5 years, CCH has invested in excess of $20 M to expand research through Children's Research Institute and the Department. Last year, CCH committed to an even more substantial expansion of facilities and faculty. Thus, we are poised to extend our successful CHRC program. We have handpicked 21 senior faculty representing 6 Departments, 3 Colleges, and 3 Institutes across Children's Research Institute and The Ohio State University to serve as Established Investigators. Furthermore, we have identified an outstanding pool of prospective scholars for this renewal application. PERFORMANCE SITE ========================================Section End===========================================