Child Health Research Career Development Award

主要研究者/项目负责人（最后一名、第一名、中间名）：汉森、托马斯N。产品说明：陈述申请的广泛的、长期的目标和具体的目的，参考项目的健康相关性。简明地描述研究设计和实现这些目标的方法。避免总结过去的成果和使用第一人称。这些摘要旨在作为与申请分开的拟议工作的简洁和准确的说明。如果申请得到资助，这种描述将成为公开的信息。因此，不包括专有/保密信息。不得超过3“HE空间PRO_/_DE_。 哥伦布儿童医院儿童健康研究职业奖（CCH-CHRCDA）的长期目标是培养新的儿科医生科学家。由于生物医学科学在过去十年中迅速发展，迫切需要加快将基础科学发现转化为有益于儿童健康的临床应用。作为一个大型的，多学科的儿科部门（俄亥俄州州立大学）在一家医院专门致力于儿童护理（CCH），我们是理想的定位，以进一步这一事业。我们将继续我们现有的CHRC的主题，为这个竞争性的更新应用-分子医学在儿科。尽管自1996年首次申请以来，科学和医学已经快速发展，但我们选择的主题的基本前提只是得到了验证。 我们为过去四年取得的成就感到自豪。我们的第一个3 CHRC学者都连续获得独立的NIH R 01资助。包括我们目前接受CHRC资助的3名学者在内，50%（3/6）是wonaen，17%（1/6）是少数民族（非洲人）。对研究和加拿大人权委员会的机构支持从未如此强大。在过去的5年里，卫生协调委员会已投资超过2000万美元，通过儿童研究所和该部扩大研究。去年，CCH致力于更大幅度地扩大设施和师资队伍。 因此，我们准备扩大我们成功的CHRC计划。我们精心挑选了21名高级教师，代表6个部门，3所学院和3所儿童研究所和俄亥俄州州立大学作为既定的调查员。此外，我们已经确定了一个优秀的未来学者池为这个更新的应用程序。性能现场=

Principal Investigator/Program Director (Last, first, middle): Hansen, Thomas N. DESCRIPTION: State the application'sbroad, long-term objectivesand specificaims, makingreference to the healthrelatednessof the project.Descdbe concisely the research designand methodsfor achievingthese goals.Avoid summariesof past accomplishmentsand the use of the first person.Thisabstractis meant to serve as a succinctand accurate descriptionof the proposedworkwhen separatedfrom the application.Ifthe applicationis funded,thisdescription,as is,will become pub_'licnformation.Therefore, do not includeproprietary/confidentiainl formation.DO NOT EXCEE¿) 3'HE SPACE PRO_/_DE_. The long-term objective of Columbus Children's Hospital Child Health Research Career Award (CCH-CHRCDA) is to train new pediatric physician-scientists. Because of rapid advances in biomedical sciences during the past decade, there is a pressing need to speed the transfer of basic science discoveries to clinical applications that will benefit the health of children. As a large, multidisciplinary Department of Pediatrics (Ohio State University) at a hospital devoted solely to the care of children (CCH), we are ideally positioned to further this cause. We will continue the theme of our existing CHRC for this competing renewal application - molecular medicine in pediatrics. Although science and medicine have moved forward at a rapid pace since our original application in 1996, the basic premise of our chosen theme has only gained validation. We are proud of our achievements over the last 4 years. Our first 3 CHRC Scholars have all in succession obtained independent NIH R01 funding. Including our 3 Scholars currently receiving CHRC funding, 50% (3/6) have been wonaen and 17% (1/6) have been minorities (African). Institutional support of research and the CHRC has never been stronger. Over the past 5 years, CCH has invested in excess of $20 M to expand research through Children's Research Institute and the Department. Last year, CCH committed to an even more substantial expansion of facilities and faculty. Thus, we are poised to extend our successful CHRC program. We have handpicked 21 senior faculty representing 6 Departments, 3 Colleges, and 3 Institutes across Children's Research Institute and The Ohio State University to serve as Established Investigators. Furthermore, we have identified an outstanding pool of prospective scholars for this renewal application. PERFORMANCE SITE ========================================Section End===========================================