Clinical Academic Oncologist Training Program

描述（由申请人提供）：威斯康星大学Paul Calabresi K12临床肿瘤学奖的目标是培养成功的、高素质的临床研究人员，他们致力于患者相关肿瘤研究的学术生涯。这些研究人员将有能力领导和管理独立的临床肿瘤学研究项目，并在合作团队环境中与基础、临床和转化研究人员进行互动。本申请描述了一个灵活的职业发展计划，具有肿瘤类型特异性，多学科的方法来进行和设计假设驱动的临床试验。为了实现这一目标，该计划的具体目标是：1)通过提供肿瘤学，生物统计学，伦理学，沟通和监管问题的指导和教学计划，培训医学，外科或放疗肿瘤学家和其他临床肿瘤学研究的适当候选人；2)培训研究人员将基础癌症研究成果转化为临床治疗试验所需的技能，以便在协作团队研究环境中有效地开展临床研究；3)通过在多学科、肿瘤类型的特定研究中获得专业知识和在职业生涯发展中获得指导，培养学术领袖。Joan Schiller博士将担任项目负责人。基于核心教学要求的个性化培训计划将与UW K30（临床研究者预备计划）一起开发。所有受训者将由临床和实验室导师以及项目负责人指导。咨询委员会将监测所有受训人员的进展情况，并评价和监测培训方案的总体效力。西华大学的其他资源将提供给学员，包括西华大学综合癌症中心、麦卡德尔癌症研究所、西华大学GCRC、I期实验治疗计划、II期临床试验联盟、西华大学生物统计学和生物医学计算资源，以及与东部合作肿瘤小组的紧密联系。自2001年5月该项目招募了第一名实习生以来，已有7人被该项目接受为临床讲师（其中4人来自西澳大学以外）。7人中有4人是女性，其中2人是美国国立卫生研究院定义的少数族裔。7人中有3人仍在训练中。在完成该项目的4人中，有3人担任教职，并活跃于临床肿瘤学研究。该申请的主要变化包括允许在临床适当的情况下使用助理教授的学术头衔。

DESCRIPTION (provided by applicant): The goal of the University of Wisconsin Paul Calabresi K12 Clinical Oncology Award is to produce successful, highly qualified clinical investigators who are committed to an academic career in patient related oncology research. These investigators will be capable of leading and managing independent clinical oncology research programs and of interacting with basic, clinical, and translational researchers in collaborative team settings. This application describes a flexible career development program with a tumor-type specific, multi-disciplinary approach to the conduct and design of hypothesis-driven clinical trials. To accomplish this goal, the specific objectives of the program are to: 1) train medical, surgical, or radiotherapy oncologists and other appropriate candidates in clinical oncology research by providing a mentoring and didactic program in oncology, biostatistics, ethics, communication, and regulatory issues; 2) train researchers in the skills necessary to translate basic cancer research results into clinical therapeutic trials, so as to work effectively in a collaborative team research setting for clinical research; and 3) develop academic leaders by acquisition of expertise in a multi-disciplinary, tumor-type specific research and by mentorship in professional career development. Dr. Joan Schiller will serve as the Program Leader. Individualized training programs, based on a core didactic requirement, will be developed in conjunction with the UW K30 (Clinical Investigator Preparatory Program). All trainees will be mentored by a clinical and lab-based mentor and the Program Leader. The Advisory Committee will monitor the progress of all trainees and evaluate and monitor overall effectiveness of the training program. Additional resources of the UW, which will be available to the trainees, include the UW Comprehensive Cancer Center, the McArdle Institute for Cancer Research, the UW GCRC, the Phase I Experimental Therapeutics Program, the Phase II Clinical Trials Consortium, UWCCC Biostatistics and Biomedical Computing resources, and strong ties to the Eastern Cooperative Oncology Group. Since this grant recruited its first trainee in May 2001, 7 individuals have been accepted into the program as clinical instructors (4 of whom were recruited from outside the UW). Four of the 7 are women, and 2 of the 7 are NIH-defined minorities. Three of the 7 are still in training. Of the 4 who have completed the program, 3 have faculty positions and are active in clinical oncology research. Major changes made to this application include allowing the academic title of Assistant Professor, where clinically appropriate.