Specimen Bank Core

样本库核心

• 批准号: 7681523
• 负责人: JOHN S GREENSPAN
• 金额: $ 18.93万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-01 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7681523
• 关键词: Aliquot; Asia; Cerebrospinal Fluid; Clinical; Clinical Research; Clinical Trials; Collaborations; Collection; Consultations; Deposition; Education; Equipment and supply inventories; Failure; Freezing; Funding; Goals; HIV; HIV Infections; Human immunodeficiency virus test; International; Investigation; Leukocytes; Oral; Plasma; Population Sciences; Procedures; Process; Research; Research Infrastructure; Research Personnel; Saliva; San Francisco; Seminal fluid; Serum; Services; Shipping; Ships; Source; Specimen; Swab; Training; Translational Research; United States National Institutes of Health; Urine; Vagina; Vaginal Douching; Whole Blood; Woman; base; cohort; member; men; mindfulness-based stress reduction; repository; sample collection; tissue fixing

The UCSF-GIVI CFAR Specimen Bank Core has since 1987 provided expertise and an infrastructure for the collection, processing and storage of biospecimens for CFAR investigators. The Specimen Bank Core, under the director of Dr. John S. Greenspan and Ms. Yvonne De Souza has provided repository services to many cohorts and clinical studies based in San Francisco, including the Women's Interagency HIV Study (WINS), Options Project (Primary HIV infection), Staying Well (Clinical trial of mindfulness-based stress reduction and education groups for HIV), SFGH Observational Cohort Evaluating Long-Term Consequences of Virologic Failure (SCOPE), and a recently funded NIH study, Men of Asia testing for HIV (MATH). The Specimen Bank Core has received over 295,000 deposits and has shipped over 275,000 specimens aliquots worldwide, including whole blood, serum, plasma, leukocytes, fresh frozen and fixed tissue, urine, saliva (stimulated and unstimulated), semen, cerebrospinal fluid, oral and vaginal mucosal swabs, and cervico-vaginal lavage. A goal of the Core is to continue its current repository functions and to further develop as a local and national source for investigators pursing translational research. Specific Aims of the Specimen Bank Core (SBC) are to: 1. Process, inventory, and store (short and long term) biospecimens collected from CFAR investigators. 2. Provide well-characterized biospecimens to support CFAR investigations and to provide specimens to non-CFAR investigators to enhance collaboration between CFAR and non-CFAR investigators. 3. Provide consultation and training for CFAR investigators seeking information on optimal specimen collection, processing, storage, and shipment. 4. Advise the International Core in specimen banking and storage procedures.

UCSF-GIVI CFAR样本库核心自1987年以来一直为 为CFAR调查人员收集、处理和储存生物标本。样本库核心， 在约翰·S·Greenspan和Yvonne De Souza女士提供了存储库服务， 许多基于旧金山弗朗西斯科的队列和临床研究，包括妇女跨部门艾滋病毒研究 （2014），选项项目（艾滋病毒感染），保持良好（正念压力的临床试验 艾滋病毒的减少和教育组），SFGH观察队列评价长期后果 病毒学失败（SCOPE），以及最近资助的NIH研究，亚洲男性艾滋病毒检测（MATH）。 标本库核心已收到超过295，000笔存款，并已运送超过275，000份标本 全球范围内的等分试样，包括全血、血清、血浆、白细胞、新鲜冷冻和固定组织、尿液， 唾液（刺激和未刺激）、精液、脑脊液、口腔和阴道粘膜拭子，以及 宫颈阴道灌洗核心的一个目标是继续其目前的存储库功能，并进一步 发展成为当地和国家的研究人员追求转化研究的来源。 样本库核心（SBC）的具体目标是： 1.处理、清点和储存（短期和长期）从CFAR调查人员收集的生物标本。 2.提供充分表征的生物标本，以支持CFAR调查，并提供标本， 非CFAR调查员，以加强CFAR和非CFAR调查员之间的合作。 3.为寻求最佳标本信息的CFAR调查人员提供咨询和培训 收集、加工、储存和运输。 4.在样本库和存储程序方面向国际核心提供建议。