Development Core

开发核心

• 批准号: 7683337
• 负责人: JANET S BUTEL
• 金额: $ 17.85万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-01 至 2010-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7683337
• 关键词: AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Address; Advisory Committees; Annual Reports; Appointment; Area; Award; Award Guidelines; Clinical Research; Communities; Consultations; Data; Development; Eligibility Determination; Extramural Activities; Faculty; Feasibility Studies; Fostering; Funding; Grant; HIV; Institution; Instruction; International; Leadership; Mentors; Monitor; Mycobacterium tuberculosis; Outcome; Peer Review; Performance; Process; Publications; Publishing; Purpose; Rate; Recommendation; Request for Applications; Research; Research Personnel; Research Project Grants; Review Committee; Site; Strategic Planning; System; Translational Research; career; follow-up; member; multidisciplinary; programs; success

The purpose of the CFAR Developmental Core is to foster the development of HIV/AIDS-related research at Baylor and UTHouston, This is accomplished in several ways, two of which are new to this resubmission. First, investigator-initiated scientific studies are supported to develop preliminary data for research applications. Types of eligible projects include pilot and feasibility studies and collaborative translational research projects. Second, a new effort, designated "Collaborative Core Initiatives", targets specific research gaps and opportunities at our CFAR. Third, also new, some funds are dedicated to support the development of Scientific Programs that draw on strengths, opportunities, and expertise at our CFAR. We have chosen to emphasize first "HIV and Coinfections", focusing on Mycobacterium tuberculosis. Awards are made following a rigorous peer review system. Funds also may be used to assist in recruitment of new faculty engaged in HIV/AIDS research. Finally, new to this application, we will provide a comprehensive mentoring program to help the career development of junior investigators involved in HIV/AIDS research. This core has an impressive record of accomplishments from the former Baylor CFAR. From 1995 to 2001, Developmental awards ($646,005) supported 33 projects on both basic and clinical research topics. Twenty-one of the 33 awardees obtained external funding totaling over $12.4 million within 3 years following their award, representing a success rate of 63% and a 19-fold leveraging of CFAR funds invested. Grantees published over 190 articles during the 3-year follow-up period. Developmental funds have also been used to assist in the recruitment of two junior faculty members. We are requesting $220,000/year in Years 11-15 to continue these developmental efforts. Allocations of Developmental funds among the various developmental programs each year will be determined by the CFAR Internal Advisory Committee. The Core is led by Dr. Janet Butel, Director, and two Associate Directors, Drs. Mary Estes (Baylor) and Mary Velasquez (UTHouston). Dr. Velasquez is a new appointment with this resubmission.

CFAR发展核心的目的是促进与艾滋病毒/艾滋病有关的发展 在贝勒大学和休斯顿大学的研究中，这是通过几种方式完成的，其中两种是新的 重新提交。首先，支持由研究人员发起的科学研究，以开发初步数据 研究应用。符合条件的项目类型包括试点和可行性研究以及合作项目 翻译研究项目。第二，一项名为“合作核心倡议”的新努力旨在 我们CFAR的具体研究差距和机会。第三，也是新的，一些基金专门用于支持 利用我们CFAR的优势、机会和专业知识开发科学项目。 我们选择首先强调“艾滋病毒和混合感染”，重点是结核分枝杆菌。 奖项的颁发遵循严格的同行审查制度。资金也可以用来协助招聘。 从事艾滋病毒/艾滋病研究的新教员。最后，对于该应用程序来说，我们将提供一个 全面的辅导计划，帮助初级调查人员的职业发展 艾滋病毒/艾滋病研究。 这一核心在前贝勒CFAR取得了令人印象深刻的成就。从1995年到 2001年，发展奖(646,005美元)资助了33个基础和临床研究主题的项目。 33名获奖者中有21名在3年内获得了总额超过1240万美元的外部资助 获奖后，CFAR的成功率为63%，投资的CFAR资金杠杆提高了19倍。 受赠者在3年的跟踪期间发表了190多篇文章。发展基金也 用于协助招聘两名初级教员。我们要求每年220,000美元 11-15年，以继续这些发展努力。发展性资金在不同国家之间的分配 每年的发展计划将由CFAR内部咨询委员会决定。《核心》 由主任珍妮特·巴特尔博士和两名副主任玛丽·埃斯蒂斯博士(贝勒)和玛丽·埃斯特斯博士领导 贝拉斯克斯(休斯顿大学)。贝拉斯克斯博士是这次重新提交的新任命。