Developmental Core

贝勒-休斯敦大学CFAR发展核心的目的是通过由调查员发起的试点项目奖励和对跨学科研究项目的支持，促进贝勒和休斯顿大学与艾滋病毒/艾滋病相关的研究的发展。这一核心有着令人印象深刻的成就记录。在目前的资助期间(2004-2008年)，60.5万美元的发展试点奖励支持了17个关于基础、临床和行为科学研究主题的项目。这些奖励导致外部资金总额为1180万美元，相当于投资的CFAR资金的近20倍杠杆作用。在CFAR成立以来的较长时期内(1995-2008年)，CFAR发展赠款产生了2430万美元的外部资金，反映了投资资金杠杆作用的18.7倍。发展核心还支持利用我们CFAR的优势、机会和专业知识的科学项目的发展。我们已经确定“艾滋病毒相关恶性肿瘤”是一个新的科学项目，它涉及到与贝勒的丹·L·邓肯癌症中心的合作。在我们的CFAR中，一个“协作核心倡议”的机制被用来瞄准特定的跨学科研究机会。发展基金每年在各种发展方案中的分配将由CFAR内部咨询委员会决定。对特定项目的奖励是在严格的同行审查制度下进行的。 CFAR发展核心计划提供全面的主动性指导计划，以帮助参与艾滋病毒/艾滋病研究的初级调查人员的职业发展；所有申请发展奖的初级教员都需要一对一的指导。 该中心由德克萨斯大学安德森癌症中心主任珍妮特·巴特尔博士和副主任贾甘纳达·萨斯特里博士领导。萨斯特里博士是这份意见书的新任命。

The purpose of the Baylor-UTHouston CFAR Developmental Core is to foster the development of HIV/AIDS-related research at Baylor and UTHouston through investigator-initiated pilot project awards and the support of interdisciplinary research projects. This Core has an impressive record of accomplishments. In the current funding period (2004-2008), $605,000 in Developmental pilot awards supported 17 projects on basic, clinical, and behavioral science research topics. These awards led to external funding totaling $11.8 million, representing nearly 20-fold leveraging of CFAR funds invested. For the longer period since the establishment of the CFAR (1995-2008), CFAR Developmental grants have resulted in external funding of $24.3 million that reflected 18.7-fold leveraging of invested funds. The Developmental Core also supports the development of Scientific Programs that draw on strengths, opportunities, and expertise at our CFAR. We have identified "HIV-Associated Malignancies" as a new Scientific Program that involves collaboration with the Dan L. Duncan Cancer Center at Baylor. A mechanism of "Collaborative Core Initiatives" is used to target specific interdisciplinary research opportunities at our CFAR. Allocations of Developmental funds among the various developmental programs each year will be determined by the CFAR Internal Advisory Committee. Awards for specific projects are made following a rigorous peer review system. The CFAR Developmental Core offers a comprehensive proactive mentoring program to assist in the career development of junior investigators involved in HIV/AIDS research; one-on-one mentoring is required for all junior faculty who apply for Developmental awards. The Core is led by Dr. Janet Butel, Director, and by Dr. Jagannadha Sastry, Associate Director, UT M.D. Anderson Cancer Center. Dr. Sastry is a new appointment with this submission.