MDIBL STEER: Pathways of Chemical Action in Human Disease

描述（由申请人提供） 山荒岛生物实验室（MDIBL）和NIEHS中心膜毒性研究（CMTS）在MDIBL提出了一个短期教育经验的研究（STEER）为六个缅因州高中学生。MDIBL STEER计划的总体目标是将选定的学生与NIEHS中心调查人员进行匹配，以获得环境健康科学方面的实践研究经验。科学主题为“人类疾病的化学作用途径”，与中心的使命一致，即在细胞和分子水平上阐明环境毒物的毒性机制和排泄途径。除了研究经验，每个学生将组装奖学金组合，包括他们的实验室笔记本，和其他组件来记录他们的奖学金。学生将参加外部活动，以丰富实验室的经验，包括期刊俱乐部会议，科学研讨会和演讲。缅因州大学的研究和评估中心将进行项目评估和分析，以及短期的学生跟踪。MDIBL将跟踪STEER参与者在完成STEER计划之后的教育和职业道路。STEER管理人员将与当地高中教师合作，他们将提名学生申请该计划，并将帮助MDIBL确定由于种族，种族或经济或教育背景不利的个人而在科学方面代表性不足的学生。MDIBL STEER计划的具体目标是：1。为缅因州高中学生提供环境健康科学的多学科研究经验，并应用于人类健康，由国家认可的基础科学家和医生科学家指导，2。作为缅因州高中学生继续在环境健康科学的本科和研究生学位课程的管道。

DESCRIPTION (provided by applicant) The Mount Desert Island Biological Laboratory (MDIBL) and the NIEHS Center for Membrane Toxicity Studies (CMTS) at MDIBL propose a Short-Term Educational Experience for Research (STEER) for six Maine high school students. The overall goal of the MDIBL STEER program is to match selected students with NIEHS Center investigators for a hands-on research experience in the environmental health sciences. The scientific theme is "Pathways of Chemical Action in Human Disease", which parallels the Center's mission to elucidate the mechanisms of toxicity and pathways of excretion of environmental toxicants at the cellular and molecular level. In addition to the research experience, each student will assemble a fellowship portfolio, including their laboratory notebook, and other components to document their fellowship. Students will participate in external activities to enrich the laboratory experience including journal club meetings, scientific seminars, and presentations. The Center for Research and Evaluation at the University of Maine will conduct program evaluation and analysis, as well as short-term student follow-up. MDIBL will track the educational and career paths of STEER participants beyond their completion of the STEER program. STEER administrators will work with local high school teachers who will nominate students to apply to the program, and who will help MDIBL identify students underrepresented in science by virtue of their ethnicity, race, or individuals from economically or educationally disadvantaged backgrounds. The specific aims of the MDIBL STEER program are: 1. To provide Maine high school students with multidisciplinary research experiences in the environmental health sciences with applications to human health, mentored by nationally recognized basic scientists and physician scientists and 2. To serve as a pipeline for Maine high school students to continue in undergraduate and graduate degree programs in the environmental health sciences.