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CORE--Mass Spectrometry

核心——质谱

基本信息

批准号：
7240046
负责人：
MAX L DEINZER
金额：
$ 21.05万
依托单位：
OREGON STATE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
起止时间：
2007-04-01 至 2010-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7240046
关键词：
Affinity Chromatography Amides Area Arts Award Biochemistry Biological Biological Markers Budgets Cartoons Cells Chemistry Complex Contracts Core Facility Data Data Analyses Deuterium Development Digestion Dissociation Education Educational workshop Electrons Environment Environmental Health Equipment Facility Construction Funding Category Foundations Funding Gases Generations Goals Grant Health Hydrogen Ionizing radiation Ions Kinetics Knowledge Label Lasers Ligand Binding Ligands Maintenance Mass Spectrum Analysis Measurement Membrane Proteins Methods Molecular Motion Nature Outcome Pathway interactions Peptides Phase Phosphorylation Physiologic pulse Pilot Projects Post Translational Modification Analysis Post-Translational Protein Processing Preparation Problem Solving Program Research Project Grants Progress Reports Protein Databases Proteins Proteomics Pulse taking Range Recording of previous events Research Research Personnel Resources Robotics SHFM1 gene Sampling Science Secure Services Site Specificity Spectrometry Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Structural Biologist Students Support of Research Techniques Time Toxicology Work base computerized data processing data modeling design and construction environmental agent environmental chemical experience improved insight instrument instrumentation ionization mass spectrometer oxidation particle programs repaired research study response skills small molecule success three dimensional structure two-dimensional

项目摘要

The Mass Spectrometry (MS) Facility Core has been established to maintain and provide the mass spectrometric and associated analytical capabilities required to support environmental health-related research conducted by EHS Center investigators, program project grant investigators, and pilot project investigators. This Core maintains state-of-the-art sample preparation and instrumental techniques that increase the sensitivity, mass range, specificity, and data processing capacity of the Core's analytical capabilities and the necessary databases for protein and organic compound identifications. In addition, this Core serves as an educational resource by providing an interdisciplinary environment in which graduate students in chemistry, biochemistry, and toxicology pursue their thesis research. The facility provides a wealth of experience in the analysis of samples as well as in the interpretation of experimental data. Finally, the facility supports the development and implementation of new mass spectrometer configurations that will advance the analysis of environmental agents as well as proteomics.

质谱（MS）设施核心已建立，以维持和提供质量支持与环境健康有关的由EHS中心调查员、计划项目资助调查员和试点项目进行的研究 investigators.该核心保持了最先进的样品制备和仪器技术，提高核心分析的灵敏度、质量范围、特异性和数据处理能力，蛋白质和有机化合物鉴定的能力和必要的数据库。此外，本发明还提供了一种方法，该核心通过提供跨学科环境作为教育资源，化学、生物化学和毒理学研究生从事论文研究。该设施提供了丰富的经验，在分析样品，以及在解释实验数据最后，该设施支持新质谱仪的开发和实施这些配置将推进环境因子和蛋白质组学的分析。