Communication Outcomes for Naming Treatments in Aphasia

失语症命名治疗的沟通结果

• 批准号: 7516607
• 负责人: Anastasia Marie Raymer
• 金额: $ 22.22万
• 依托单位: OLD DOMINION UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-01 至 2013-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7516607
• 关键词: Academic Research Enhancement Awards; Acquired Aphasia; Activities of Daily Living; Address; Affect; Anomia; Aphasia; Behavior Therapy; Clinical Trials; Communication; Daily; Development Plans; Effectiveness; Experimental Designs; Failure; Gestures; Goals; Health; Impairment; Individual; Inferior; Language; Language Disorders; Lead; Left; Left cerebral hemisphere; Life; Link; Measures; Methods; Modeling; Names; Nickel; Outcome; Participant; Patients; Pattern; Process; Production; Public Health; Purpose; Randomized Clinical Trials; Rate; Research; Research Design; Retrieval; Sampling; Semantics; Speech Therapy; Staging; Stroke; Symptoms; Testing; Thinking; Training; Treatment Protocols; Treatment outcome; World Health Organization; base; disability; follow-up; frontal lobe; lexical; neuroimaging; prospective; response; treatment effect

DESCRIPTION (provided by applicant): Thousands of individuals each year suffer a stroke affecting the left hemisphere of the brain and develop aphasia, an acquired language disability. One of the most common symptoms of aphasia is word retrieval impairment, which can disrupt the ability to express even basic thoughts and needs. Several behavioral treatment methods have been described that have positive impact on word retrieval abilities, largely in constrained picture naming tasks. The true impact of treatment gains need to be appreciated as well during conversational word retrieval, that is, at the level of communication activities/participation (WHO, 2001). Much less evidence is available about the most effective treatments leading to positive outcomes in discourse level- communication. Further, word retrieval treatment studies have often shown largest treatment effects in individuals with mild-to-moderate impairments, often characterized by failure in lexical phonologic stages of word retrieval, and more limited effects in individuals with severe semantically-based word retrieval impairments. That is, those with the greatest needs to communicate, if only with single words, have the poorest response to word retrieval treatment. The purpose of this project is to investigate modified versions of two word retrieval treatment approaches, errorless naming treatment and verbal+gestural treatment, for their effects not only for picture naming, but also for measures of communication activities/participation. Further, we will examine treatment outcomes in individuals with phonologic and semantic word retrieval impairments. Because our treatments are still in exploratory stages of development, we plan to test 16 participants, 8 in each treatment protocol, using single participant multiple baseline experimental designs replicated across word sets and participants. Half of the participants receiving each treatment will have semantically-based impairments. We will examine the effects of our treatments for word retrieval and gesture production in picture naming and discourse samples, as well as in communication rating scales measured at treatment completion and at one month follow up. Finally, we will compare outcomes for picture naming probes administered daily versus those administered at pre- and post- treatment to determine any impact of this errorful research design for errorless training. PUBLIC HEALTH RELEVANCE: Hundreds of thousands of individuals are living with the consequences of stroke, including aphasia, an impairment in the ability to understand and express oneself through words and sentences. This project aims to identify more effective methods of speech therapy to assist individuals who are recovering from stroke and aphasia to maximize their ability to express ideas and basic needs during daily life activities.

描述（由申请人提供）：每年有数千人遭受影响大脑左半球的中风并发展为失语症，这是一种获得性语言障碍。失语症最常见的症状之一是单词提取障碍，这可能会破坏表达甚至基本思想和需求的能力。已经描述了几种行为治疗方法，对单词检索能力有积极的影响，主要是在受约束的图片命名任务中。在会话词汇检索过程中，也就是在交流活动/参与一级，也需要认识到治疗收益的真正影响（卫生组织，2001年）。更少的证据是关于最有效的治疗方法，导致积极的结果，在话语层面-沟通。此外，单词检索治疗研究往往表现出最大的治疗效果在个人与轻度至中度的障碍，往往以失败为特征的词汇语音阶段的单词检索，和更有限的效果在个人与严重的语义为基础的单词检索障碍。也就是说，那些最需要交流的人，如果只是用单个单词，对单词检索治疗的反应最差。本研究的目的是探讨两种词提取处理方法的改进版本，即无错命名处理和言语+手势处理，不仅对图片命名，而且对交流活动/参与的测量都有影响。此外，我们将研究治疗结果与语音和语义词检索障碍的个人。由于我们的治疗仍处于探索性开发阶段，我们计划测试16名参与者，每个治疗方案8名，使用跨单词集和参与者复制的单参与者多基线实验设计。接受每种治疗的参与者中有一半会有基于语义的障碍。我们将研究我们的治疗的效果，在图片命名和话语样本中的单词检索和手势制作，以及在治疗完成时和一个月随访时测量的沟通评级量表。最后，我们将比较每天给予图片命名探针与治疗前和治疗后给予图片命名探针的结果，以确定这种错误的研究设计对无错误训练的任何影响。公共卫生关系：成千上万的人生活在中风的后果中，包括失语症，这是一种通过单词和句子理解和表达自己的能力受损。本项目旨在寻找更有效的言语治疗方法，帮助中风和失语症康复者最大限度地提高他们在日常生活活动中表达思想和基本需求的能力。