REACH-OUT CHICAGO CHILDRENS DIABETES PREVENTION PROJECT

接触芝加哥儿童糖尿病预防项目

• 批准号: 7431674
• 负责人: DEBORAH BURNET
• 金额: $ 47.66万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-30 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7431674
• 关键词: Address; Adolescent; Adult; African American; Age; Area Under Curve; Behavior Therapy; Behavioral; Biochemical Markers; Body Weight decreased; Body fat; Body measure procedure; Caring; Chicago; Child; Childhood; Clinical; Communities; Control Groups; Cost Analysis; Cost Measures; Data; Development; Diabetes Mellitus; Diabetes prevention; Eating; Effectiveness of Interventions; End Point; Epidemiologic Studies; Exercise; Family; Fasting; Glucose; Habits; Health; Health Educators; Health system; High Fiber Diet Low Fat; Hispanics; Hour; Incidence; Insulin; Interdisciplinary Study; Intervention; Life Style; Measures; Medical; Minority; Minority Groups; Modeling; Non-Insulin-Dependent Diabetes Mellitus; Numbers; OGTT; Obesity; Outcome Measure; Overweight; Parents; Participant; Pattern; Pediatrics; Personal Satisfaction; Physical activity; Physiological; Population; Prevention; Program Effectiveness; Psychological reinforcement; Randomized; Recruitment Activity; Research; Research Proposals; Resources; Risk; Risk Factors; Sampling; Side; Standards of Weights and Measures; Study Subject; Surrogate Endpoint; Testing; Translational Research; Universities; Weight; Weight Gain; Work; Youth; base; cost; cost effectiveness; design; diabetes prevention program; diabetes risk; glucose tolerance; grandparent; improved; inner city; insight; insulin sensitivity; modifiable risk; nutrition; obesity risk; prevent; programs; theories; trend; type 2 diabetes in children

DESCRIPTION (provided by applicant): The association between obesity and the development of type 2 diabetes mellitus is well documented from physiological and epidemiological studies. As overweight is on the rise in the pediatric population due to high fat, low fiber diets and decreased physical activity, type 2 diabetes is becoming more prevalent in young people, especially among minority youth. As shown in the adult Diabetes Prevention Program, healthy nutrition and exercise habits and weight loss can effectively decrease the risk of type 2 diabetes. In pediatrics, programs to modify nutrition and lifestyle habits in order to decrease overweight have been shown to work best when they involve children and parents (or grandparents) together. These interventions need to be culturally and age appropriate. The proposed REACH-OUT Chicago Children's Diabetes Prevention Project is a community-based, family-oriented health program, grounded in behavioral theory and supported by empirical data, to decrease overweight and risk of type 2 diabetes in young people from the high risk, mainly African American population served by and surrounding The University of Chicago. The intervention was developed and pilot tested using insights from formative research within this community, so as to be culturally appropriate. Our specific aims are: (1) To test a culturally sensitive, community-based, family oriented intervention to decrease obesity and risk of type 2 diabetes in a high risk inner-city African American population using outcomes that measure body habitus, biochemical markers of insulin sensitivity, and measures of lifestyle habits, and (2) To evaluate the within-trial cost-effectiveness of this program, from the health system perspective. This program of translational research is designed through multidisciplinary collaboration within The University of Chicago and within the community we serve and is designed to address the needs of children and families within the cultural context of our community.

描述（由申请人提供）： 肥胖与2型糖尿病的发展之间的关联是从生理和流行病学研究中充分证明的。由于高脂肪，低纤维饮食和体育锻炼的降低，小儿种群的超重正在增长，因此2型糖尿病在年轻人中变得越来越普遍，尤其是在少数族裔青年中。如《成人糖尿病预防计划》中所示，健康的营养和运动习惯和体重减轻可以有效地降低2型糖尿病的风险。在儿科中，为了减少超重而修改营养和生活方式习惯的计划在让孩子和父母（或祖父母）一起参与时表现出最好的作用。这些干预措施必须在文化上是适当的。拟议中的芝加哥儿童糖尿病预防项目是一项基于社区的，面向家庭的健康计划，以行为理论为基础，并得到经验数据的支持，可降低来自高风险的年轻人的超重和2型糖尿病风险，主要是芝加哥大学和周围的非裔美国人人口。开发了干预措施，并使用该社区内形成性研究的见解进行了测试，以便在文化上适当。我们的具体目的是：（1）测试一种具有文化敏感的，基于社区的，面向家庭的干预措施，以降低高风险的高风险内城非美国非洲人人口中2型糖尿病的风险，使用衡量身体习惯的结果，生物化学标记，胰岛素敏感性的生化标志，以及对生活方式的成本效果，以及在这种成本中的衡量标记，并构成了这种成本的效果。这项翻译研究计划是通过芝加哥大学和我们服务的社区中的多学科合作设计的，旨在满足我们社区文化背景下儿童和家庭的需求。