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Center for Genetic Research, Ethics, and Law

基因研究、伦理和法律中心

基本信息

批准号：
7273722
负责人：
Eric T Juengst
金额：
$ 107.27万
依托单位：
CASE WESTERN RESERVE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2004
资助国家：
美国
起止时间：
2004-09-01 至 2009-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7273722
关键词：
Address Agreement Architecture Attitude Belief Cardiology Cereals Clinical Clinical Investigator Collaborations Communities Complex Condition Creativeness Critiques Disclosure Elements Ethics Exercise Family Family Relationship Figs - dietary Fostering Foundations Gene Transfer Gene Transfer Techniques Genetic Genetic Enhancement Genetic Research Genetic Variation Genome Genomics Goals Haplotypes Health Benefit Health Sciences Human Human Biology Human Genetics Imagination Incentives Individual Industry Informed Consent Interdisciplinary Study International Knowledge Laws Legal Life Maps Mediating Medicine Mind Mission Molecular Medicine Morals Outcome Outcomes Research Parasitology Participant Pathway interactions Policies Policy Maker Policy Making Population Privacy Process Public Health Publications Range Reaction Regulation Research Research Design Research Ethics Research Ethics Committees Research Personnel Research Project Grants Research Training Resources Rights Risk Scholarship Science Science Policy Scientist Shapes Social Values Social Welfare Speed Structure Students System Technology Thinking Tissues Training Programs Translations Variant Work base commercialization cost cultural values design ethical legal social implication experience genetic pedigree genome-wide analysis human study improved innovation interest lens novel practical application programs social success tool trait

项目摘要

DESCRIPTION (provided by applicant): The mission of the proposed Center for Genetics Research Ethics and Law (CGREL) is to foster sustained interdisciplinary research on the ethical, legal, and social issues involved in the design and conduct of human genetics research with individuals, families, communities, and populations. CWRU already hosts a variety of research efforts relevant to the CGREL's theme. The CGREL will integrate these efforts to launch new research collaborations and provide the resource structure necessary for their application to high priority genetics research policy questions. The basic architecture of the CGREL consists of six overlapping research groups, six research resource cores, and a research training program. The research collaborations generated by the CGREL will be harnessed to pursue four Center-Wide research aims, which we believe reflect the highest priority needs in genetic research ethics and policymaking: 1. To improve our understanding of the relationship between human genetics research and the humans it seeks to benefit by elucidating the cultural values and beliefs that influence different people's reactions to and experience of genetics research participation. 2. To improve our understanding of the relationship between human genetics research and the human benefits it promises by elucidating the influence of translational incentives, ranging from commercial prospects to benefit-sharing agreements, on the design and conduct of basic genetics research. 3. To anticipate the research ethics and science policy issues raised by new advances in genetics research by analyzing the confluence of human variation research, computational genomics, sequencing technologies, and gene transfer techniques through the lenses of contemporary research regulations and norms. 4. To harness ongoing scholarship on genetics research ethics for practical application by providing evidence-based policy options for use by the scientific community, institutional review boards, and national research regulatory bodies in seeking to improve participant protections in the design and conduct of human genetic research.

描述（由申请人提供）：拟议中的遗传学研究伦理与法律中心（CGREL）的使命是促进涉及个人、家庭、社区和人群的人类遗传学研究的设计和实施中涉及的伦理、法律和社会问题的持续跨学科研究。CWRU已经主持了与CGREL主题相关的各种研究工作。CGREL将整合这些努力，启动新的研究合作，并提供必要的资源结构，使其应用于高优先级的遗传学研究政策问题。