Center for Genetic Research, Ethics, and Law

基因研究、伦理和法律中心

• 批准号: 8074754
• 负责人: Eric T Juengst
• 金额: $ 6.37万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-01 至 2010-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8074754
• 关键词: Agreement; Architecture; Belief; Collaborations; Communities; Family; Fostering; Gene Transfer Techniques; Genetic Research; Genomics; Human; Human Genetics; Incentives; Individual; Interdisciplinary Study; Laws; Mission; Participant; Policies; Population; Reaction; Regulation; Research; Research Ethics; Research Ethics Committees; Research Training; Resources; Scholarship; Science Policy; Structure; Technology; Training Programs; Variant; benefit sharing; cultural values; design; ethical legal social implication; evidence base; experience; improved; lens; practical application

DESCRIPTION (provided by applicant): The mission of the proposed Center for Genetics Research Ethics and Law (CGREL) is to foster sustained interdisciplinary research on the ethical, legal, and social issues involved in the design and conduct of human genetics research with individuals, families, communities, and populations. CWRU already hosts a variety of research efforts relevant to the CGREL's theme. The CGREL will integrate these efforts to launch new research collaborations and provide the resource structure necessary for their application to high priority genetics research policy questions. The basic architecture of the CGREL consists of six overlapping research groups, six research resource cores, and a research training program. The research collaborations generated by the CGREL will be harnessed to pursue four Center-Wide research aims, which we believe reflect the highest priority needs in genetic research ethics and policymaking: 1. To improve our understanding of the relationship between human genetics research and the humans it seeks to benefit by elucidating the cultural values and beliefs that influence different people's reactions to and experience of genetics research participation. 2. To improve our understanding of the relationship between human genetics research and the human benefits it promises by elucidating the influence of translational incentives, ranging from commercial prospects to benefit-sharing agreements, on the design and conduct of basic genetics research. 3. To anticipate the research ethics and science policy issues raised by new advances in genetics research by analyzing the confluence of human variation research, computational genomics, sequencing technologies, and gene transfer techniques through the lenses of contemporary research regulations and norms. 4. To harness ongoing scholarship on genetics research ethics for practical application by providing evidence-based policy options for use by the scientific community, institutional review boards, and national research regulatory bodies in seeking to improve participant protections in the design and conduct of human genetic research.

描述（由申请人提供）：拟议中的遗传学研究伦理与法律中心（CGREL）的使命是促进涉及个人、家庭、社区和人群的人类遗传学研究的设计和实施中涉及的伦理、法律和社会问题的持续跨学科研究。CWRU已经主持了与CGREL主题相关的各种研究工作。CGREL将整合这些努力，启动新的研究合作，并提供必要的资源结构，使其应用于高优先级的遗传学研究政策问题。