LSI Doctoral Training Centres: University of Leeds

LSI 博士培训中心：利兹大学

• 批准号: EP/F500033/1
• 负责人: Peter Olmsted
• 金额: $ 141.68万
• 依托单位: University of Leeds
• 依托单位国家: 英国
• 项目类别: Training Grant
• 财政年份: 2007
• 资助国家: 英国
• 起止时间: 2007 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FF500033%2F1
• 关键词: LSI; Doctoral; Training; Centres; University

Under the title Physical Science for Bio-molecular Interactions in Cells and their Environments , this centre will train doctoral scientists in basic and emerging techniques, experimental and theoretical, that address a focussed set of target problems in post-genome life science and bio-nanotechnology at the level of biomolecules and cells. The emergent techniques available include optical tweezers, AFM, fluorescence and time-resolved EM for single molecule studies, advanced analytical tools, confocal microscopy, Terahertz spectroscopy, biophotonics, neutron and x-ray scattering, molecular dynamics and statistical mechanics of biological systems. Target problem areas include nucleic acids, proteins, complexes, membranes, vesicles, aggregated protein states and biominearlisationThe need for such training has been clearly identified in the UK (EPSRC LSI mission statement, BBSRC) and also underpins the development of basic technologies across growth sectors of new technology. It shares methodology with acknowledged best practice in LSI activities in the USA (Scripps, Rockerfeller Inst.) and in Europe (Munich, Dresden, Curie Inst.)

在细胞及其环境中生物分子相互作用的物理科学的标题下，该中心将在基础和新兴技术，实验和理论方面培养博士科学家，这些技术在生物分子和细胞水平上解决后基因组生命科学和生物纳米技术中的一系列目标问题。现有的新兴技术包括用于单分子研究的光镊、AFM、荧光和时间分辨EM、先进的分析工具、共聚焦显微镜、太赫兹光谱学、生物光子学、中子和X射线散射、分子动力学和生物系统的统计力学。目标问题领域包括核酸、蛋白质、复合物、膜、囊泡、聚集蛋白质状态和生物微生物学。在英国已经明确了对此类培训的需求（EPSRC LSI使命声明，BBSRC），并且还支持新技术增长部门的基础技术开发。它与美国LSI活动中公认的最佳实践分享方法（Scripps，Rockerfeller Inst.）和欧洲（慕尼黑、德累斯顿、居里研究所）